Abstract
We report a case of a 59-year-old male patient with a postoperative fungal infection of the left eye. A dark-pigmented yeast, Exophiala dermatitidis (previously known as Wangiella dermatitidis), was identified from the culture of the biopsy taken from the posterior capsule. The infection was successfully eradicated by a combination of surgical and medical (i.e., voriconazole and fluconazole) treatment. This is the first report of successfully treated E. dermatitidis endophthalmitis, which demonstrates that a prompt and aggressive antifungal therapy combined with surgical intervention is necessary to prevent vision loss in cases of endophthalmitis due to Exophiala species. Beside the case description, we also aim to provide a literature review of previously reported eye infections caused by Exophiala species in order to help the future diagnosis and management of the disease.
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Acknowledgements
This study was supported by the “Lendület” Grant of the Hungarian Academy of Sciences (LP2016-8/2016) and the Project GINOP-2.3.2-15-2016-00035 (Széchenyi 2020 Programme). LG is supported by the Postdoctoral Excellence Programme (PD 120808) of the Hungarian National Research, Development and Innovation Office (NKFI Office). PM would like to thank Deanship of Scientific Research at Majmaah University, Kingdom of Saudi Arabia, for supporting this work under Project No. 37/106.
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Mónika Homa and Palanisamy Manikandan have been contributed equally to this work.
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Homa, M., Manikandan, P., Saravanan, V. et al. Exophiala dermatitidis Endophthalmitis: Case Report and Literature Review. Mycopathologia 183, 603–609 (2018). https://doi.org/10.1007/s11046-017-0235-4
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DOI: https://doi.org/10.1007/s11046-017-0235-4