Abstract
In February 2012, a district health authority received three inmates with bilateral leg swelling and difficulty in breathing from a detention camp for unauthorized immigrants. A case control study was conducted. Fasting blood samples of case and control groups were collected according to instructions of the laboratory for determining thiamine level, and their 1 week dietary intake was analyzed. 9% (21/226) of inmates had bilateral leg swelling, and 75% (6/8) of them had low thiamine level (< 66 mmol/L). Their diet contained mainly polished rice and other items with low thiamine contents. Bilateral leg swelling was associated with history of no meat consumption during past 3 months (OR 8.4; CI 2.2–32.1). Patients were treated with 100 mg thiamine intravenously and 5 mg orally per day for 6 weeks. All patients responded well. The management was advised to provide vitamin B complex daily, and encouraged to provide thiamine rich foods.
References
Nguyen PAH, Pittayawonganon C, Praekunatham H, Thitichai P, Shen T, Lwin NN, et al. Beriberi outbreak among factory workers in Chachoengsao Province, Thailand, 2012–2013. OSIR. 2014;7(3):1–7. http://www.osirjournal.net/index.php/osir/article/view/35.
Cerroni MP, Barrado JC, Nobrega AA, Lins AB, da Silva IP, Mangueira RR, et al. Outbreak of beriberi in an Indian population of the upper Amazon region, Roraima State, Brazil, 2008. Am J Trop Med Hyg. 2010;83(5):1093–7.
Jeyakumar D. Thiamine responsive ankle oedema in detention centre inmates. Med J Malays 1995;50(1):17–20.
Chang TP, Kit KK, Aun TB, Nagaraj S, Peng TN, Zulkifli SN. Socio-economic development and mortality patterns and trends in Malaysia. Asia Pac Popul J. 1987;2(1):3–20.
Fozi K, Azmi H, Kamariah H, Azwa MS. Prevalence of Thiamine deficiency at a drug rehabilitation centre in Malaysia. Med J Malaysia 2006; 61(5):519–25.
Doung-ngern P, Kesornsukhon S, Kanlayanaphotporn J, Wanadurongwan S, Songchitsomboon S. Beriberi outbreak among commercial fishermen, Thailand 2005. Southeast Asian J Trop Med Public Health. 2007;38(1):130–5.
Chen KT, Twu SJ, Chiou ST, Pan WH, Chang HJ, Serdula MK. Outbreak of beriberi among illegal mainland Chinese immigrants at a detention centre in Taiwan. Public Health Rep. 2003;118(1):59–64.
Naidoo DP, Gathiram V, Sadhabiriss A, Hassen F. Clinical diagnosis of cardiac beriberi. S Afr Med J. 1990;77(3):125–7.
Carpenter KJ. A short history of nutritional science: part 2 (1885–1912). J Nutr. 2003;133(4):975–84.
Coats D, Shelton-Dodge K, Ou K, Khun V, Seab S, Sok K, Prou C, Tortorelli S, Moyer Cooper LE, Tadhg P, Begley TP, Enders F. Fischer PR, Topazian M. Thiamine deficiency in Cambodian infants with and without beriberi. J Pediatr. 2012;161:843–7.
Acknowledgements
We thank the Director General of the Ministry of Health, Malaysia. We also express our gratitude to the State Health Office, District Health Office and the Authority of Detention Camp. We would also like to thank everyone who supported this outbreak investigation.
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Abdul Rahman, S., Jeffree, M.S., Kamaludin, F. et al. Beriberi Outbreak Among Unauthorised Immigrants in a Detention Camp in Malaysia. J Immigrant Minority Health 20, 1294–1297 (2018). https://doi.org/10.1007/s10903-017-0674-5
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DOI: https://doi.org/10.1007/s10903-017-0674-5