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A comparative study of two presbyopia-correcting intraocular lenses combining bifocal and extended depth-of-focus profiles

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Abstract

Objective

To compare the visual performance of two presbyopia-correcting intraocular lenses (IOLs) that combine both bifocal and extended depth-of-focus profiles, Artis® Symbiose® Plus (Symbiose Plus; Cristalens Industrie, Lannion, France) and Tecnis® Synergy® (Synergy; Johnson & Johnson Vision, Santa Ana, CA, USA).

Methods

The medical records of patients with cataract bilaterally implanted with either Symbiose Plus or Synergy between January 2022 and January 2023 were assessed. The principal measures of postoperative findings included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near (40 and 33 cm) visual acuity (UNVA), objective optical quality (OOQ) parameters, distance-corrected defocus curve analysis, and surveys of subjective satisfaction.

Results

Total of 96 eyes from 48 patients were enrolled. Each group was equally composed of 24 patients, 48 eyes. There were no significant differences between the two groups on baseline characteristics. Both IOLs displayed excellent binocular UDVA, CDVA, and UNVA (40 and 33 cm) with no statistical difference (p = 0.467(UDVA), p = 0.584(CDVA), p = 0.096(40-cm UNVA), and p = 0.621(33-cm UNVA)). However, with regard to UIVA, the Synergy group showed significantly superior results (p < 0.001). In contrast, the Symbiose Plus group showed significantly better results on OOQ parameters and patient-reported quality of vision survey outcomes (both p < 0.001).

Conclusions

Both IOLs provided a decent continuous range of vision from near to far distance.

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Funding

No funding was received for the research, authorship, or publication of this article.

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Authors and Affiliations

  1. Department of Ophthalmology, Kim’s Eye Hospital, Konyang University College of Medicine, 136 Youngshinro, Youngdeungpo-gu, Seoul, 07301, Republic of Korea

    Jeongmin Kim, Hungwon Tchah & Kyungmin Koh

  2. Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea

    Tae-im Kim & Kyoung Yul Seo

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  1. Jeongmin Kim
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  2. Tae-im Kim
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  3. Kyoung Yul Seo
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  4. Hungwon Tchah
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Contributions

JK, TK acquired and analyzed the data, drafted the initial manuscript, and revised the manuscript. KYS, HT, and KK conceptualized and designed the study, and collected data. TK, KK, and JK conceptualized and designed the study, coordinated, and supervised data collection, analyzed the data, critically reviewed the manuscript, and revised the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Kyungmin Koh.

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Appendix: modified Korean version of the Visual Function Index (VF-14)

Appendix: modified Korean version of the Visual Function Index (VF-14)

  1. 1.

    How often do you wear glasses?

    Never () Occasionally() Sometimes () Often () Always ()

  2. 2.

    If you need glasses, when do you need them most?

    Not applicable () at a near distance () at a distance ()

  3. 3-1.

    Do you have any difficulty, without glasses, reading small print, such as labels on medicine bottles, a telephone book, or food labels?

    Never () Occasionally () Sometimes () Often () Always ()

  4. 3-2.

    Do you have any difficulty, even with glasses, reading small print, such as labels on medicine bottles, a telephone book, of food labels?

    Not applicable () Never () Occasionally () Sometimes () Often () Always ()

  5. 4-1.

    Do you have any difficulty, without glasses, reading a newspaper or a book?

    Never () Occasionally () Sometimes () Often () Always ()

  6. 4-2.

    Do you have any difficulty, even with glasses, reading a newspaper or a book?

    Not applicable () Never () Occasionally () Sometimes () Often () Always ()

  7. 5.

    Do you have any difficulty, even with glasses, recognizing people when they are close to you?

    Never () Occasionally () Sometimes () Often () Always ()

  8. 6.

    Do you have any difficulty, even with glasses, seeing steps, stairs, or curbs?

    Never () Occasionally () Sometimes () Often () Always ()

  9. 7.

    Do you have any difficulty, even with glasses, watching television?

    Never () Occasionally () Sometimes () Often () Always ()

  10. 8.

    Do you have any difficulty, even with glasses, doing fine handwork like sewing, knitting, crocheting, carpentry?

    Never () Occasionally () Sometimes () Often () Always ()

  11. 9.

    Do you have any difficulty, even with glasses, taking part in sports like bowling, handball, tennis, golf?

    Never () Occasionally () Sometimes () Often () Always()

  12. 10.

    How much difficulty do you have driving during the day because of your vision?

    Never () Occasionally () Sometimes () Often () Always ()

  13. 11.

    How much difficulty do you have driving at night because of your vision?

    Never () Occasionally () Sometimes () Often () Always ()

  14. 12-1.

    If you have any discomfort, what are the symptoms?

    None () Glare () Shadows () Unwanted images ()

  15. 12-2.

    If you have any other discomfort, please write.

  16. 13.

    How satisfied are you with your operation?

    Completely satisfied () Very satisfied () Moderate () Poor () Unsatisfied ()

  17. 14.

    Are you more satisfied than you would be after having only one eye operation after a bilateral operation? (Only if applicable)

    Completely satisfied () Very satisfied () Moderate () Poor () Unsatisfied ()

  18. 15.

    Would you recommend this surgery to someone else?

    Strongly not recommend () Not recommend () Recommend () Strongly recommend ()

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Kim, J., Kim, Ti., Seo, K.Y. et al. A comparative study of two presbyopia-correcting intraocular lenses combining bifocal and extended depth-of-focus profiles. Int Ophthalmol 44, 54 (2024). https://doi.org/10.1007/s10792-024-02979-0

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