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Orbital myositis associated with celiac disease

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Abstract

A 26-year-old female patient presented with redness, lid edema on the right eye and diplopia on left gaze. There was a minimal limitation of adduction of the right eye, accompanied with pain and diplopia. Orbital magnetic resonance imaging confirmed the diagnosis of orbital myositis. Anti-endomysial immunoglobulin (Ig) A, anti-endomysial IgG, anti-gliadin IgA and anti-tissue transglutaminase IgG antibodies were positive, while other tests for autoimmune diseases were unremarkable. The patient stated that her diarrhea had been relieved by a gluten-free diet. Methylprednisolone therapy (1 mg/kg) was started and on her next visit her complaints were relieved. Later, methotrexate (15 mg/week) was added to the therapy as the patient became steroid-dependent, and she has been attack-free for the last 3 months under methotrexate and low-dose methylprednisolone (4 mg/day) treatment. Associations between orbital myositis and various autoimmune diseases have previously been reported. We report here the first case of associated orbital myositis and celiac disease.

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Acknowledgments

We thank Prof. Dr. Haner Direskeneli for his valuable advice on the management of this patient and critical reading of this manuscript.

Conflict of interest

The authors declare no conflict of interest.

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Authors and Affiliations

  1. Department of Ophthalmology, Marmara University School of Medicine, Istanbul, Turkey

    Eren Cerman, Fehim Esen, Muhsin Eraslan & Haluk Kazokoglu

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  1. Eren Cerman
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  2. Fehim Esen
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  3. Muhsin Eraslan
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  4. Haluk Kazokoglu
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Correspondence to Eren Cerman.

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Cerman, E., Esen, F., Eraslan, M. et al. Orbital myositis associated with celiac disease. Int Ophthalmol 34, 635–638 (2014). https://doi.org/10.1007/s10792-013-9824-5

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  • DOI: https://doi.org/10.1007/s10792-013-9824-5

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