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Uranium: an overview of physicochemical properties, exposure assessment methodologies, and health effects of environmental and occupational exposure

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Abstract

Uranium is chemo- and radiotoxic element which can cause multifactorial health hazards. Natural and anthropogenic uranium contamination raises concerns about potential public health problems. Natural contamination plays a significant role with regard to uranium exposure in the general population, whereas anthropogenic contamination leads to occupational uranium exposure, particularly in nuclear industry workers. In this review, we present a state-of-the-art status concerning uranium-induced health risks with a focus on epidemiological findings of uranium processing and enrichment plant workers. We provide a general overview of physicochemical properties of uranium and analytical methods for measuring or monitoring uranium, describe environmental and occupational exposure scenarios, and discuss the challenges for objectively investigating risks from uranium exposure.

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Acknowledgements

The authors would like to thank three anonymous journal reviewers for providing valuable insights that greatly improved this manuscript.

Funding

This research was undertaken thanks in part to funding from the Canada First Research Excellence Fund through the Arthur B. McDonald Canadian Astroparticle Physics Research Institute.

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AMR, SV, MK, MIL, KS conceptualized; AMR conducted literature survey and drafted; MIL, MK, SV reviewed and supervised the drafting of the manuscript. AMR and KS constructed the figures. All authors contributed to the article and approved the submitted version.

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Correspondence to Matthew I. Leybourne.

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The authors have no relevant financial or non-financial interests to disclose. The authors have no competing interests to declare that are relevant to the content of this article. All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or nonfinancial interest in the subject matter or materials discussed in this manuscript. The authors have no financial or proprietary interests in any material discussed in this article. The authors have no conflicts of interest.

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Rathod, A.M., Verpaele, S., Kelvin, M. et al. Uranium: an overview of physicochemical properties, exposure assessment methodologies, and health effects of environmental and occupational exposure. Environ Geochem Health 45, 1183–1200 (2023). https://doi.org/10.1007/s10653-022-01293-x

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  • DOI: https://doi.org/10.1007/s10653-022-01293-x

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