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A new 3,4-dihydroisocoumarin isolated from Botryosphaeria sp. F00741

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Chemistry of Natural Compounds Aims and scope

A new 3,4-dihydroisocoumarin, named botryoisocoumarin A (1), was obtained from the fermentation culture of Botryosphaeria sp. F00741, together with two known ones, 3,8-dihydroxy-3-methylisochroman-1-one (2) and 4,8-dihydroxy-3-methylisochroman-1-one (3). Their structures were elucidated by spectroscopic analyses, including 1D and 2D NMR experiments and ESI mass spectrometry, and by comparison with those reported. Compound 1 was evaluated for its antitumor and antimicrobial activities in vitro.

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Acknowledgment

This work was financially supported by the Key Grant of Chinese Ministry of Education (306010) and the 863 Program (2006AA10A202).

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Authors and Affiliations

  1. Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, No. 422 South Siming Road, Xiamen, Fujian, 361005, P. R. China

    Yuhang Xu, Chunhua Lu & Zhonghui Zheng

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  1. Yuhang Xu
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  2. Chunhua Lu
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  3. Zhonghui Zheng
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Correspondence to Zhonghui Zheng.

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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2012, pp. 190–191.

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Xu, Y., Lu, C. & Zheng, Z. A new 3,4-dihydroisocoumarin isolated from Botryosphaeria sp. F00741. Chem Nat Compd 48, 205–207 (2012). https://doi.org/10.1007/s10600-012-0205-5

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  • DOI: https://doi.org/10.1007/s10600-012-0205-5

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