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Effects of a Combined Exercise Training Program on Health Indicators and Quality of Life of People Living with HIV: A Randomized Clinical Trial

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Abstract

The aim of this study was to evaluate the effects of 16 weeks of combined exercise training (CET) on muscle strength, body composition, depression, anxiety and quality of life of people living with HIV (PLHIV). Twenty-three participants completed the study, 14 in trained group (TG) and 9 in control group (CG). TG consisted of resistance and aerobic training three times a week, while the CG was exposed to recreational activities twice a week. CET promoted increased muscle strength (25% in overall strength) and aerobic capacity (+ 20% in training speed and + 23% in VO2 during aerobic training; p < 0.05). In addition, TG had better quality of life and reduced depression rates (from 7 subjects with mild, moderate or severe depression to 1 post-training). In conclusion, this pilot data demonstrated that 16 weeks of CET increased muscle strength, and improved depression and quality of life indexes in a small sample of PLHIV.

Resumen

El objetivo de este estudio fue evaluar los efectos de 16 semanas de entrenamiento combinado (CET) sobre la fuerza muscular, composición corporal, depresión, ansiedad y calidad de vida de las personas que viven con el VIH (PVHIV). Veintitrés participantes completaron el estudio, 14 en el grupo entrenado (TG) y 9 en el grupo control (CG). TG consistió en entrenamiento de resistencia y aeróbico tres veces por semana, mientras que el CG estuvo expuesto a actividades recreativas dos veces por semana. CET promovió una mayor fuerza muscular (25% en la fuerza general) y la capacidad aeróbica (+ 20% en la velocidad de entrenamiento y + 23% en el VO2 durante el entrenamiento aeróbico; p < 0.05). Además, TG tenía una mejor calidad de vida y tasas de depresión reducidas (de 7 sujetos con depresión leve, moderada o severa a 1 post entrenamiento). En conclusión, estos datos piloto demostraron que 16 semanas de CET aumentaron la fuerza muscular y mejoraron los índices de depresión y calidad de vida en una pequeña muestra de PVHIV.

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Acknowledgements

The authors thank all the staff from the University Hospital services for helping to recruit the subjects and providing the medical records, the staff that helped with the training, and a special thanks to the subjects of the study. This work was supported by Brazilian grants from SETI (Secretaria da Ciência, Tecnologia e Ensino Superior do Paraná).

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Authors and Affiliations

  1. Department of Physical Education, Faculty of Physical Education and Sport, State University of Londrina, Rodovia Celso Garcia Cid | Pr 445 Km 380 | Campus Universitário, Londrina, Paraná, Brazil

    Vitor H. F. Oliveira & Rafael Deminice

  2. Filadélfia University, Londrina, PR, Brazil

    Flávia T. Rosa

  3. Department of Psychology, State University of Londrina, Londrina, PR, Brazil

    Jádia C. Santos

  4. University Hospital, Institute of Health Science, State University of Londrina, Londrina, PR, Brazil

    Susana L. Wiechmann & Argéria M. S. Narciso

  5. Department of Physiology, State University of Maringá, Maringá, PR, Brazil

    Solange M. Franzoi de Moraes

  6. Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA

    Allison R. Webel

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  1. Vitor H. F. Oliveira
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Correspondence to Rafael Deminice.

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Oliveira, V.H.F., Rosa, F.T., Santos, J.C. et al. Effects of a Combined Exercise Training Program on Health Indicators and Quality of Life of People Living with HIV: A Randomized Clinical Trial. AIDS Behav 24, 1531–1541 (2020). https://doi.org/10.1007/s10461-019-02678-3

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