Abstract
Studies show the importance of the personal experience of meaning in life for older adults, but adults with dementia have been largely excluded from this research. The current study examined the longitudinal predictive effect of meaning in life for the psychological and cognitive functioning of older adults with Alzheimer’s disease and whether cognitive decline predicted presence of meaning in life. On three yearly measurement occasions, presence of meaning in life, depressive symptoms, life satisfaction, and cognitive functioning were assessed in structured interviews with a convenience sample of 140 older adults with Alzheimer’s disease from nine nursing homes in Belgium. Cross-lagged panel and latent growth curve models were used to analyze the longitudinal relationships between the variables. Over the three measurement waves, participants with higher presence of meaning reported lower depressive symptoms one year later. Presence of meaning and life satisfaction predicted each other over time, but only between the first and second wave. The analyses showed no strong evidence for a longitudinal association between meaning in life and cognitive functioning in either direction. The findings emphasize the importance of the experience of meaning in life for the psychological functioning of older adults with Alzheimer’s disease. The lack of evidence for associations between meaning and cognitive functioning questions the prevailing view that intact cognitive abilities are a necessity for experiencing meaning. More attention to the potential of meaning interventions for persons with dementia is warranted.
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Notes
Main deviations: level of education was not mentioned as covariate in the pre-registration but was included as control because of its association with cognitive functioning (inclusion did not alter main conclusions). Separate models 2–4 were not specified in the pre-registration but were added because of more acceptable parameters-observations ratio.
Crosstabs showed that those with missing data on PoMT1 also had a higher rate of dropping out of the study due to death (47%) than those with PoMT1 data available (27%). However, when drop-out due to death was investigated as outcome in a logistic regression, PoMT1 missingness was not predictive of drop-out over and above the predictive effect of age, which suggests that the association between PoM missingness and dropout due to death is likely attributable to participant age (i.e., older participants are more likely to have missing PoMT1 data and are more likely to drop out due to death). Full crosstabs and logistic regression output can be found on OSF (osf.io/czvhb).
While the longitudinal associations between SWLS and MMSE and between GDS and MMSE were not the main focus of this manuscript, we tested these separate cross-lagged models as well for exploratory purposes. We found no significant cross-lagged relationships between SWLS and MMSE or between GDS and MMSE.
References
Boyle PA, Buchman AS, Barnes LL, Bennett DA (2010) Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons. Arch Gen Psychiatr 67(3):304. https://doi.org/10.1001/archgenpsychiatry.2009.208
Ching-Teng Y, Ya-Ping Y, Chia-Ju L, Hsiu-Yueh L (2020) Effect of group reminiscence therapy on depression and perceived meaning of life of veterans diagnosed with dementia at veteran homes. Soc Work Health Care 59(2):75–90. https://doi.org/10.1080/00981389.2019.1710320
Czekierda K, Banik A, Park CL, Luszczynska A (2017) Meaning in life and physical health: systematic review and meta-analysis. Health Psychol Rev 11(4):387–418
Dewing J (2007) Participatory research: a method for process consent with persons who have dementia. Dementia 6(1):11–25. https://doi.org/10.1177/1471301207075625
Dewitte L, Vandenbulcke M, Dezutter J (2019) Meaning in life matters for older adults with Alzheimer’s disease in residential care: associations with life satisfaction and depressive symptoms. Int Psychogeriatr. https://doi.org/10.1017/S1041610218002338
Dezutter J, Luyckx K, Wachholtz A (2015) Meaning in life in chronic pain patients over time: associations with pain experience and psychological well-being. J Behav Med 38(2):384–396
Diener E, Emmons RA, Larsen RJ, Griffin S (1985) The satisfaction with life scale. J Pers Assess 49(1):71–75. https://doi.org/10.1207/s15327752jpa4901_13
Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12(3):189–198
Frankl VE (1968) Man’s search for meaning: an introduction to logotherapy. Hodder and Stoughton, London
Fritze F, Ehrt U, Hortobagyi T, Ballard C, Aarsland D (2011) Depressive symptoms in Alzheimer’s disease and Lewy body dementia: a one-year follow-up study. Dement Geriatr Cogn Disord 32(2):143–149. https://doi.org/10.1159/000332016
Fry PS (2000) Religious involvement, spirituality and personal meaning for life: existential predictors of psychological wellbeing in community-residing and institutional care elders. Aging Ment Health 4(4):375–387. https://doi.org/10.1080/713649965
Garland EL, Farb NA, Goldin RP, Fredrickson BL (2015) Mindfulness broadens awareness and builds eudaimonic meaning: a process model of mindful positive emotion regulation. Psychol Inq 26(4):293–314. https://doi.org/10.1007/s12671-014-0341-z
Gendlin ET (1962/1997) Experiencing and the creation of meaning: A philosophical and psychological approach to the subjective. Northwestern University Press, Evanston, IL
George DR (2011) Intergenerational volunteering and quality of life: mixed methods evaluation of a randomized control trial involving persons with mild to moderate dementia. Qual Life Res 20(7):987–995. https://doi.org/10.1007/s11136-010-9837-8
Gerstorf D, Lövdén M, Röcke C, Smith J, Lindenberger U (2007) Well-being affects changes in perceptual speed in advanced old age: Longitudinal evidence for a dynamic link. Dev Psychol 43(3):705. https://doi.org/10.1037/0012-1649.43.3.705
Gleeson H, Hafford-Letchfield T, Quaife M, Collins DA, Flynn A (2019) Preventing and responding to depression, self-harm, and suicide in older people living in long term care settings: a systematic review. Aging Ment Health 23(11):1467–1477. https://doi.org/10.1080/13607863.2018.1501666
Greenberg LS, Pascual-Leone J (2001) A dialectical constructivist view of the creation of personal meaning. J Constr Psychol 14(3):165–186. https://doi.org/10.1080/10720530125970
Hamaker EL, Kuiper RM, Grasman RP (2015) A critique of the cross-lagged panel model. Psychol Methods 20(1):102. https://doi.org/10.1037/a0038889
Haugan G (2014) Meaning-in-life in nursing-home patients: a correlate with physical and emotional symptoms. J Clin Nurs 23(7–8):1030–1043. https://doi.org/10.1111/jocn.12282
Heintzelman SJ, King LA (2013) On knowing more than we can tell: intuitive processes and the experience of meaning. J Posit Psychol 8(6):471–482. https://doi.org/10.1080/17439760.2013.830758
Hill CE, Kline KV, Miller M, Marks E, Pinto-Coelho K, Zetzer H (2019) Development of the meaning in life measure. Couns Psychol Q 32(2):205–226. https://doi.org/10.1080/09515070.2018.1434483
Holst G, Hallberg IR (2003) Exploring the meaning of everyday life, for those suffering from dementia. Am J Alzheimers Dis Other Demen 18(6):359–365. https://doi.org/10.1177/153331750301800605
Hooker SA, Masters KS, Park CL (2018) A meaningful life is a healthy life: a conceptual model linking meaning and meaning salience to health. Rev Gen Psychol 22(1):11–24. https://doi.org/10.1037/gpr0000115
Hoyl M, Alessi CA, Harker JO, Josephson KR, Pietruszka FM, Koelfgen M, Mervis JR, Fitten LJ, Rubenstein LZ (1999) Development and testing of a five-item version of the geriatric depression scale. J Am Geriatr Soc 47(7):873–878
Irving J, Davis S, Collier A (2017) Aging with purpose: systematic search and review of literature pertaining to older adults and purpose. Int J Aging Hum Dev 85(4):403–437. https://doi.org/10.1177/0091415017702908
Jayawickreme E, Forgeard MJ, Seligman ME (2012) The engine of well-being. Rev Gen Psychol 16(4):327–342. https://doi.org/10.1037/a0027990
Jongenelis K, Gerritsen D, Pot A, Beekman A, Eisses A, Kluiter H, Ribbe M (2007) Construction and validation of a patient-and user-friendly nursing home version of the geriatric depression scale. Int J Geriatr Psychiatry 22(9):837–842. https://doi.org/10.1002/gps.1748
Kim G, Shin SH, Scicolone MA, Parmelee P (2019) Purpose in life protects against cognitive decline among older adults. Am J Geriatr Psychiatry 27(6):593–601. https://doi.org/10.1016/j.jagp.2019.01.010
Kline RB (2005) Principles and practice of structural equation modeling, 2nd edn. The Guilford Press, New York
Kontos PC (2004) Ethnographic reflections on selfhood, embodiment and Alzheimer’s disease. Ageing Soc 24(6):829–849. https://doi.org/10.1017/S0144686X04002375
Krause N (2007) Thought suppression and meaning in life: a longitudinal investigation. Int J Aging Hum Dev 64(1):67–82. https://doi.org/10.2190/2044-390U-7106-5610
Mak W (2011) Self-reported goal pursuit and purpose in life among people with dementia. J Gerontol B Psychol Sci Soc Sci 66B(2):177–184. https://doi.org/10.1093/geronb/gbq092
Martela F, Steger MF (2016) The three meanings of meaning in life: distinguishing coherence, purpose, and significance. J Posit Psychol 11(5):531–545. https://doi.org/10.1080/17439760.2015.1137623
McKnight PE, Kashdan TB (2009) Purpose in life as a system that creates and sustains health and well-Being: an integrative, testable theory. Rev Gen Psychol 13(3):242–251. https://doi.org/10.1037/a0017152
Park CL, Knott CL, Williams RM, Clark EM, Williams BR, Schulz E (2020) Meaning in life predicts decreased depressive symptoms and increased positive affect over time but does not buffer stress effects in a national sample of African-Americans. J Happiness Stud. https://doi.org/10.1007/s10902-019-00212-9
Phinney A (2011) Horizons of meaning in dementia: Retained and shifting narratives. J Relig Spirit Aging 23(3):254–268. https://doi.org/10.1080/15528030.2011.563210
Raymaekers K, Luyckx K, Moons P (2020) A guide to improve your causal inferences from observational data. Eur J Cardiovasc Nurs. https://doi.org/10.1177/1474515120957241
Reker GT, Wong PTP (2012) Personal meaning in life and psychosocial adaptation in the later years. In: Wong PTP (ed) The human quest for meaning: Theories, research, and applications. 2nd edn. Routledge New York, pp 433–456
Rosseel Y (2012) Lavaan: an R package for structural equation modeling and more Version 0.5–12 (BETA). J Stat Softw 48(2):1–36. https://doi.org/10.18637/jss.v048.i02
Steger MF (2012) Experiencing meaning in life: optimal functioning at the nexus of well-being, psychopathology, and spirituality. In: Wong PTP (ed) The human quest for meaning: theories, research, and applications, 2nd edn. Routledge, New York, pp 165–184
Steger MF, Samman E (2012) Assessing meaning in life on an international scale: psychometric evidence for the meaning in life questionnaire-short form among chilean households. Int J Wellbeing 2(3):182–195. https://doi.org/10.5502/ijw.v2.i3.2
Sutin AR, Stephan Y, Terracciano A (2018) Psychological well-being and risk of dementia. Int J Geriatr Psychiatry 33(5):743–747. https://doi.org/10.1002/gps.4849
Sutin AR, Luchetti M, Stephan Y, Terracciano A (2020) Meaning in life and risk of cognitive Impairment: a 9-year prospective study in 14 countries. Arch Gerontol Geriatr. https://doi.org/10.1016/j.archger.2020.104033
Svanström R, Sundler AJ (2015) Gradually losing one’s foothold–A fragmented existence when living alone with dementia. Dementia 14(2):145–163
Takkinen S, Ruoppila I (2001) Meaning in life in three samples of elderly persons with high cognitive functioning. Int J Aging Hum Dev 53(1):51–73. https://doi.org/10.2190/WBUG-NRKM-XJ7A-5QWP
Van der Heyden K, Dezutter J, Beyers W (2015) Meaning in life and depressive symptoms: a person-oriented approach in residential and community-dwelling older adults. Aging Ment Health 19(12):1063–1070. https://doi.org/10.1080/13607863.2014.995589
Vess M, Hoeldtke R, Leal SA, Sanders CS, Hicks JA (2017) The subjective quality of episodic future thought and the experience of meaning in life. J Posit Psychol 13(4):419–428. https://doi.org/10.1080/17439760.2017.1291851
Volkert J, Härter M, Dehoust MC, Ausín B, Canuto A, Da Ronch C, Suling A, Grassi L, Munoz M, Santos-Olmo AB (2019) The role of meaning in life in community-dwelling older adults with depression and relationship to other risk factors. Aging Ment Health 23(1):100–106. https://doi.org/10.1080/13607863.2017.1396576
Wilson RS, Boyle PA, Segawa E, Yu L, Begeny CT, Anagnos SE, Bennett DA (2013) The influence of cognitive decline on well-being in old age. Psychol Aging 28(2):304
Wu LF, Koo M (2016) Randomized controlled trial of a six-week spiritual reminiscence intervention on hope, life satisfaction, and spiritual well-being in elderly with mild and moderate dementia. Int J Geriatr Psychiatry 31(2):120–127. https://doi.org/10.1002/gps.4300
Yang B, Yu H, Xing M, He R, Liang R, Zhou L (2017) The relationship between cognition and depressive symptoms, and factors modifying this association, in Alzheimer’s disease: a multivariate multilevel model. Arch Gerontol Geriatr 72:25–31. https://doi.org/10.1016/j.archger.2017.05.003
Acknowledgements
We wish to thank the participating residential care settings and residents. We thank Lotte Van Looy and Tine Schellekens for their help in collecting the data.
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This work was supported by the Research Foundation Flanders under grant 1109417 N (to LD).
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L. Dewitte, M. Vandenbulcke, and J. Dezutter designed the study and formulated the research questions. P.L Hill and L. Dewitte designed the analysis plan. L. Dewitte collected and analyzed the data and wrote the manuscript. J. Dezutter and M. Vandenbulcke supervised the data collection and provided critical feedback on the manuscript. P.L. Hill assisted with the analyses and writing of the manuscript.
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Dewitte, L., Hill, P.L., Vandenbulcke, M. et al. The longitudinal relationship between meaning in life, depressive symptoms, life satisfaction, and cognitive functioning for older adults with Alzheimer’s disease. Eur J Ageing 19, 1155–1166 (2022). https://doi.org/10.1007/s10433-022-00689-z
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DOI: https://doi.org/10.1007/s10433-022-00689-z