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3D-printed microfluidic manipulation device integrated with magnetic array

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Abstract

This paper reported a transparent, high-precision 3D-printed microfluidic device integrated with magnet array for magnetic manipulation. A reserved groove in the device can well constrain the Halbach array or conventional alternating array. Numerical simulations and experimental data indicate that the magnetic flux density ranges from 30 to 400 mT and its gradient is about 0.2–0.4 T/m in the manipulation channel. The magnetic field parameters of Halbach array in the same location are better than the other array. Diamagnetic polystyrene beads experience a repulsive force and move away from the magnetic field source under the effect of negative magnetophoresis. It is undeniable that as the flow rate increases, the ability of Halbach array to screen particle sizes decreases. Even so, it has a good particle size discrimination at a volumetric flow rate of 1.08 mL/h, which is much larger than that of a conventional PDMS device with a single magnet. The observed particle trajectories also confirm these statements. The deflection angle is related to the magnetic field, flow rate, and particle size. This 3D-printed device integrated with Halbach array offers excellent magnetic manipulation performance.

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Acknowledgements

Financial support from the National Natural Science Foundation of China (Grant No. 11572309 and 11572310), and the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDB22040502) are gratefully acknowledged. This study was also supported by the Collaborative Innovation Center of Suzhou Nano Science and Technology. Thanks to the instrumentation support from engineering practice center of USTC. This work was partially carried out at the USTC Center for Micro and Nanoscale Research and Fabrication.

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Authors and Affiliations

  1. CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technological of China, Hefei, 230027, People’s Republic of China

    Jie Wu, Yiwen Cui, Shouhu Xuan & Xinglong Gong

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  1. Jie Wu
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  2. Yiwen Cui
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  3. Shouhu Xuan
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  4. Xinglong Gong
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Correspondence to Xinglong Gong.

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Wu, J., Cui, Y., Xuan, S. et al. 3D-printed microfluidic manipulation device integrated with magnetic array. Microfluid Nanofluid 22, 103 (2018). https://doi.org/10.1007/s10404-018-2123-8

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