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How to standardize measurement of global longitudinal strain

  • Special Feature: Review Article
  • Update on Reference Values for Echocardiography
  • Published:
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Abstract

Global longitudinal strain (GLS) is a robust and sensitive marker of left-ventricular systolic function, reflecting longitudinal shortening of the ventricle. A growing body of evidence indicates its superiority in identifying subclinical, early alterations in cardiac function compared to traditional markers, such as ejection fraction. Therefore, there is a growing demand to assess GLS in clinical settings, but limited availability on how to obtain GLS accurately and appropriately in the current literature. This review summarizes key aspects of GLS measurement, including image acquisition, post-processing, and training/experience needed to facilitate the clinical implication with standardization.

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Funding

Dr. K Negishi is supported by a Fellowship (Award Reference No. 101868) from the National Heart Foundation of Australia, which had no role in the preparation of this manuscript.

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Authors and Affiliations

  1. Faculty of Medicine and Health, Charles Perkins Centre Nepean, Sydney Medical School Nepean, Nepean Hospital, The University of Sydney, Level 5 South Block, Kingswood, NSW, 2747, Australia

    Tomoko Negishi & Kazuaki Negishi

  2. Nepean Hospital, Kingswood, NSW, Australia

    Tomoko Negishi & Kazuaki Negishi

  3. Menzies Research Institute, University of Tasmania, Hobart, Australia

    Tomoko Negishi & Kazuaki Negishi

Authors
  1. Tomoko Negishi
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  2. Kazuaki Negishi
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Correspondence to Kazuaki Negishi.

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The authors declares that there are no conflicts of interest.

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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. Informed consent was obtained from all patients for being included in the study.

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Negishi, T., Negishi, K. How to standardize measurement of global longitudinal strain. J Med Ultrasonics 49, 45–52 (2022). https://doi.org/10.1007/s10396-021-01160-9

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  • DOI: https://doi.org/10.1007/s10396-021-01160-9

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