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The prevalence of gout in mainland China from 2000 to 2016: a systematic review and meta-analysis

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Abstract

Background

The prevalence of gout varied in different populations and it appeared to be increasing in the past decades. Gout is a serious health issue and is an independent risk factor for heart failure and metabolic. Therefore, we have used the method of meta-analysis to systematically evaluate the prevalence of gout in mainland China and have provided relevantly informative data for gout prevention and control.

Methods

Relevant articles from 2000 to 2016 October were identified by searching four electronic databases: PubMed, Chinese WanFang, CNKI, and Chongqing VIP. All of the calculations were performed using the MetaAnalyst beta 3.13 and R3.3 software.

Results

In all, 30 eligible articles (1 in English and 29 in Chinese) were included with a total sample size of 146,081. The pooled prevalence of gout was 1.1% (95% CI: 0.8%, 1.5%). Subgroup analysis showed the following results: 1.7 and 0.5% for male and female; 1.3 and 1.0% for inland and coast, respectively; 1.4, 1.0 and 0.7% for urban, city and rural areas; 1.0 and 1.6% for community and hospital; 1.2, 1.7, and 0.8% for eastern, central and western region; 1.0, 1.1 and 1.3% for 2000–2005, 2006–2009 and 2010–2016, respectively.

Conclusion

The prevalence of gout in mainland China is an ascendant trend that differs according to sex and region.

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Authors and Affiliations

  1. Guangxi Autonomous Regional Center for Disease Control and Prevention, Nanning, 530028, China

    Yuzhu Chen, Zhenzhu Tang, Zhaoyong Huang, Weiwen Zhou, Zhongyou Li & Xiaopeng Li

  2. Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Centre, Beijing, 100191, China

    Feng Sun

  3. Department of Population Medicine, Harvard Medical School, 401 Park Drive, Suite 401, Boston, MA, 02215, USA

    Feng Sun

Authors
  1. Yuzhu Chen
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  2. Zhenzhu Tang
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  3. Zhaoyong Huang
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  4. Weiwen Zhou
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  5. Zhongyou Li
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  6. Xiaopeng Li
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  7. Feng Sun
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Correspondence to Feng Sun.

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This study was not funded

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The authors declare that there is no conflict of interests regarding the publication of this paper.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was not obtained from all individual participants included in the study, because it is secondary source.

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Chen, Y., Tang, Z., Huang, Z. et al. The prevalence of gout in mainland China from 2000 to 2016: a systematic review and meta-analysis. J Public Health 25, 521–529 (2017). https://doi.org/10.1007/s10389-017-0812-5

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  • DOI: https://doi.org/10.1007/s10389-017-0812-5

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