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Intereye comparison of visual field progression in eyes with open-angle glaucoma

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To investigate the intereye correlations between and differences in the rates of visual field (VF) progression in eyes with bilateral open-angle glaucoma.

Study design

Retrospective, longitudinal, observational study.

Methods

Patients with bilateral open-angle glaucoma with 8 or more reliable 30 − 2 standard automated perimetry tests over a period of more than 2 years were enrolled. The rate of change of the MD (MD slope) was used as the indicator for the rates of VF progression. Descriptive statistics of the absolute intereye difference in the MD slope values were computed. Factors associated with a large intereye difference (> 0.42 dB/year) were explored.

Results

One hundred eighty-eight eyes from 94 patients (56 women) were enrolled. A significant intereye correlation of the rates of visual field progression (P = .002) was found. The mean ± standard deviation and median intereye differences of the MD slope values were 0.29 ± 0.31 and 0.18 dB/year (range: 0–1.41), respectively. The 5th, 10th, 25th, 75th, 90th, and 95th percentiles of intereye differences were 0.01, 0.02, 0.08, 0.42, 0.72, and 0.91 dB/year, respectively. Older age and slower progression were significantly associated with large intereye difference.

Conclusion

A significant intereye correlation in the rate of VF progression was found in eyes with bilateral open-angle glaucoma. We showed the distributions and associated factors of intereye differences in VF progression. These data may be used for improving the estimation of rates of VF progression.

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Authors and Affiliations

  1. Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan

    Misa Morota, Atsuya Miki, Aki Tanimura, Sanae Asonuma, Tomoyuki Okazaki, Rumi Kawashima, Shinichi Usui, Kenji Matsushita & Kohji Nishida

  2. Department of Myopia Control Research, Aichi Medical University Medical School, Nagakute, Aichi, Japan

    Atsuya Miki

  3. Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan

    Kohji Nishida

  4. Department of Ophthalmology, Aichi Medical University Medical School, 1-1 Yazako-Karimata, Nagakute, 480-1195, Aichi, Japan

    Atsuya Miki

Authors
  1. Misa Morota
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  2. Atsuya Miki
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  7. Shinichi Usui
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Corresponding author

Correspondence to Atsuya Miki.

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Conflicts of interest

M. Morota, None; A. Miki, None; A. Tanimura, None; S. Asonuma, None; T. Okazaki, None; R. Kawashima, None; S. Usui, None; K. Matsushita, None; K. Nishida, None.

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Corresponding Author: Atsuya Miki

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Morota, M., Miki, A., Tanimura, A. et al. Intereye comparison of visual field progression in eyes with open-angle glaucoma. Jpn J Ophthalmol 67, 312–317 (2023). https://doi.org/10.1007/s10384-023-00982-z

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  • DOI: https://doi.org/10.1007/s10384-023-00982-z

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