Skip to main content

Advertisement

SpringerLink
Log in

Quality of view through extended depth of focus intraocular lens in a model eye

  • Laboratory Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To compare the quality of images viewed through an extended depth of focus (EDF) intraocular lens (IOL) to that through multifocal or monofocal IOL.

Study design

Experimental study

Methods

EDF IOL (Symfony®, ZXR00V, Johnson & Johnson Vision), diffractive multifocal (ZLB00, + 3.25D or ZMB00, + 4.0D), or monofocal (ZCB00V) IOL with a spherical power of + 20.0 diopter (D) was placed in a fluid-filled model eye with corneal aberrations similar to those of human eyes. A United States Air Force Resolution Grating Target was glued to the posterior surface of the model eye and viewed through a flat contact lens, a 60D or 128D wide-angle non-contact lens (Resight®) or wide-angle contact lens (MiniQuad®). The contrast of the grating images recorded with the EDF and multifocal IOLs were compared to those through the monofocal IOL.

Results

The grating images viewed through the flat contact lens were slightly blurred when viewed through the EDF IOL but clearer than those through the multifocal IOLs with very blurred images in the periphery. The contrast of the images viewed through the EDF and multifocal IOLs through the flat contact lens was significantly lower than through the monofocal IOL (P < 0.02). The contrast of the images viewed through the EDF IOL with 60D or 128D wide-angle non-contact lens was significantly lower than through the monofocal IOL (P < 0.05) but not with wide-angle contact lens.

Conclusion

Our results suggest that vitreous surgeons can accomplish a clearer view during vitrectomy in EDF IOL-implanted eyes with a wide-angle viewing contact lens and a flat contact lens than in multifocal IOL-implanted eyes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Kollbaum PS, Bradley A. Correction of presbyopia: old problems with old (and new) solutions. Clin Exp Optom. 2020;103:21–30.

    Article  Google Scholar 

  2. Khandelwal SS, Jun JJ, Mak S, Booth MS, Shekelle PG. Effectiveness of multifocal and monofocal intraocular lenses for cataract surgery and lens replacement: a systematic review and meta-analysis. Graefes Arch Clin Exp Ophthalmol. 2019;257:863–75.

    Article  Google Scholar 

  3. Alio JL, Plaza-Puche AB, Férnandez-Buenaga R, Pikkel J, Maldonado M. Multifocal intraocular lenses: an overview. Surv Ophthalmol. 2017;62:611–34.

    Article  Google Scholar 

  4. Cochener B, Concerto Study Group. Clinical outcomes of a new extended range of vision intraocular lens: International Multicenter Concerto Study. J Cataract Refract Surg. 2016;42:1268–75.

    Article  Google Scholar 

  5. Kohnen T, Böhm M, Hemkeppler E, Schönbrunn S, Nina DeLorenzo N, Petermann K, et al. Visual performance of an extended depth of focus intraocular lens for treatment selection. Eye (Lond). 2019;33:1556–63.

    Article  Google Scholar 

  6. Breyer DRH, Kaymak H, Ax T, Kretz FTA, Auffarth GU, Hagen PR. Multifocal intraocular lenses and extended depth of focus intraocular lenses. Asia Pac J Ophthalmol (Phila). 2017;6:339–49.

    Google Scholar 

  7. Pedrotti E, Bruni E, Bonacci E, Ribeiro FJ. Comparative analysis of the clinical outcomes with a monofocal and an extended range of vision intraocular lens. J Refract Surg. 2016;32:436–42.

    Article  Google Scholar 

  8. Pedrotti E, Carones F, Aiello F, Mastropasqua R, Bruni E, Bonacci E, et al. Comparative analysis of visual outcomes with 4 intraocular lenses: monofocal, multifocal, and extended range of vision. J Cataract Refract Surg. 2018;44:156–67.

    Article  Google Scholar 

  9. Yoo YS, Whang WJ, Byun YS, Piao JJ, Kim DY, Joo CK, et al. Through-focus optical bench performance of extended depth-of-focus and bifocal intraocular lenses compared to a monofocal lens. J Refract Surg. 2018;34:236–43.

    Article  Google Scholar 

  10. Millán MS, Vega F. Extended depth of focus intraocular lens: chromatic performance. Biomed Opt Express. 2017;8:4294–309.

    Article  Google Scholar 

  11. Akella SS, Juthani VV. Extended depth of focus intraocular lenses for presbyopia. Curr Opin Ophthalmol. 2018;29:318–22.

    Article  Google Scholar 

  12. Pilger D, Homburg D, Brockmann T, Torun N, Bertelmann E, Sonnleithner C, et al. Clinical outcome and higher order aberrations after bilateral implantation of an extendeddepth of focus intraocular lens. Eur J Ophthalmol. 2018;28:425–32.

    Article  Google Scholar 

  13. Black S. A clinical assessment of visual performance of combining the TECNIS® Symfony Extended Range of Vision IOL (ZXR00) with the +3.25 D TECNIS Multifocal 1-piece IOL (ZLB00) in subjects undergoing bilateral cataract extraction. Clin Ophthalmol. 2018;12:2129–36.

    Article  Google Scholar 

  14. Böhm M, Petermann K, Hemkeppler E, Kohnen T. Defocus curves of 4 presbyopia-correcting IOL designs: diffractive panfocal, diffractive trifocal, segmental refractive, and extended-depth-of-focus. J Cataract Refract Surg. 2019;45:1625–36.

    Article  Google Scholar 

  15. Cochener B, Boutillier G, Lamard M, Auberger-Zagnoli C. A comparative evaluation of a new generation of diffractive trifocal and extended depth of focus intraocular lenses. J Refract Surg. 2018;34:507–14.

    Article  Google Scholar 

  16. de Medeiros AL, de Araujo Rolim AG, Pimenta Motta AF, Bruna Vieira Ventura BV, Vilar C, Dias Chaves MAP, et al. Comparison of visual outcomes after bilateral implantation of a diffractive trifocal intraocular lens and blended implantation of an extended depth of focus intraocular lens with a diffractive bifocal intraocular lens. Clin Ophthalmol. 2017;11:1911–6.

    Article  Google Scholar 

  17. Gatinel D, Loicq J. Clinically relevant optical properties of bifocal, trifocal, and extended depth of focus intraocular lenses. J Refract Surg. 2016;32:273–80.

    Article  Google Scholar 

  18. Ruiz-Mesa R, Abengózar-Vela A, Ruiz-Santos M. A comparative study of the visual outcomes between a new trifocal and an extended depth of focus intraocular lens. Eur J Ophthalmol. 2018;28:182–7.

    Article  Google Scholar 

  19. Rodov L, Reitblat O, Levy A, Assia EI, Kleinmann G. Visual outcomes and patient satisfaction for trifocal, extended depth of focus and monofocal intraocular lenses. J Refract Surg. 2019;35:434–40.

    Article  Google Scholar 

  20. Charles S, Runge P. Vitreoretinal complications of multifocal intraocular lenses. In: Maxwell A, Nordan LT, editors. Multifocal Intraocular Lenses. Thorofare: Slack, Inc.; 1991. p. 209–18.

    Google Scholar 

  21. Mainster MA, Reichel E, Warren KA, Harrington PG. Ophthalmoscopy and vitreoretinal surgery in patients with an ARRAY refractive multifocal intraocular lens implant. Ophthalmic Surg Lasers. 2002;33:74–6.

    Article  Google Scholar 

  22. Kawamura R, Inoue M, Shinoda K, Bissen-Miyajima H. Intraoperative findings during vitreous surgery after implantation of diffractive multifocal intraocular lens. J Cataract Refract Surg. 2008;34:1048–9.

    Article  Google Scholar 

  23. Yoshino M, Inoue M, Kitamura N, Bissen-Miyajima H. Diffractive multifocal intraocular lens interferes with intraoperative view. Clin Ophthalmol. 2010;4:467–9.

    PubMed  PubMed Central  Google Scholar 

  24. Inoue M, Noda T, Mihashi T, Ohnuma K, Bissen-Miyajima H, Hirakata HA. Quality of image of grating target placed in model of human eye with corneal aberrations as observed through multifocal intraocular lenses. Am J Ophthalmol. 2011;151:644–52.

    Article  Google Scholar 

  25. Inoue M, Noda T, Ohnuma K, Bissen-Miyajima H, Hirakata A. Quality of image of grating target placed in vitreous of isolated pig eyes photographed through different implanted multifocal intraocular lenses. Acta Ophthalmol. 2011;89:561–6.

    Article  Google Scholar 

  26. Chalam KV, Shah VA. Optics of wide-angle panoramic viewing system-assisted vitreous surgery. Surv Ophthalmol. 2004;49:437–45.

    Article  Google Scholar 

  27. Shah VA, Chalam KV. Self-stabilizing wide-angle contact lens for vitreous surgery. Retina. 2003;23:667–9.

    Article  Google Scholar 

  28. Inoue M, Noda T, Ohnuma K, Bissen-Miyajima H, Hirakata A. Quality of image of grating target placed in model eye and observed through toric intraocular lenses. Am J Ophthalmol. 2013;155:243–52.

    Article  Google Scholar 

Download references

Acknowledgements

The authors thank Professor Emeritus Duco Hamasaki of the Bascom Palmer Eye Institute, University of Miami, Miami, Florida, for discussions and thorough editing of the manuscript. The IOLs used in the study were donated by Johnson & Johnson vision.

Author information

Authors and Affiliations

  1. Kyorin Eye Center, School of Medicine, Kyorin University, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan

    Makoto Inoue, Nina Teresa Aicher, Yuji Itoh & Akito Hirakata

  2. Department of Ophthalmology, Tokyo Dental College Suidobashi Hospital, Tokyo, Japan

    Makoto Inoue & Hiroko Bissen-Miyajima

  3. Medical School, PMU-Paracelsus Medical University of Salzburg, Salzburg, Austria

    Nina Teresa Aicher

Authors
  1. Makoto Inoue
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Nina Teresa Aicher
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yuji Itoh
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hiroko Bissen-Miyajima
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Akito Hirakata
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Makoto Inoue.

Ethics declarations

Conflicts of interest

M. Inoue, Non-financial support, Lecture fee (AMO), Grant, Lecture fee (Alcon), Lecture fee (Novartis, Santen, Senju, Zeiss, Bayer); N. T. Aicher, None; Y. Itoh, Grant (Bayer), Lecture fee (Alcon, Novartis, Bayer, Santen); H. B. Miyajima, Grant, Consultant fee (AMO), Grant (Alcon, HOYA, Santen), Consultant fee (Alcon, HOYA, Zeiss), Lecture fee (Alcon, AMO, HOYA, Santen, Senju, Kowa, Zeiss); A. Hirakata, Grant (Santen), Lecture fee (Santen, Alcon, Novartis, Bayer, Sanwa Kagaku Kenkyusho, Kowa, Senju).

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Corresponding Author: Makoto Inoue

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Inoue, M., Aicher, N.T., Itoh, Y. et al. Quality of view through extended depth of focus intraocular lens in a model eye. Jpn J Ophthalmol 65, 569–580 (2021). https://doi.org/10.1007/s10384-021-00813-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10384-021-00813-z

Keywords

Search

Navigation