Abstract
To assess the surgical outcomes in patients who underwent femtosecond laser-assisted lamellar keratoplasty with double continuous suture for keratoconus, 100 patients (102 eyes) with keratoconus in advanced stages undergoing femtosecond laser-assisted lamellar keratoplasty in Shandong Eye Hospital were studied. In the management of keratoconus, 50 patients (52 eyes) received double continuous suture, and 50 patients (50 eyes) underwent interrupted suture. The follow-up duration was 1 year. Best-corrected visual acuity (BCVA), corneal astigmatism, cosmetic outcomes, and surgical complications were measured as outcome indicators. The epithelium healed at 3 ± 2 days and 4 ± 2 days in the double continuous suture group and the interrupted suture groups, respectively (P > 0.05). At 6 months after surgery, the average visual acuity was 20/125 and 20/100 (P > 0.05), and the average BCVA was 20/32 and 20/40 (P > 0.05), respectively. At 1 year after surgery, the average visual acuity was 20/63 and 20/80 (P > 0.05), and the average BCVA was 20/32 and 20/25 (P > 0.05), respectively; the mean curvature was 43.24 ± 5.15 D and 43.31 ± 5.58 D (P > 0.05), the mean astigmatism was 3.21 ± 1.74 D and 5.35 ± 1.37 D (P < 0.05).The looseness of sutures were found in 2 patients and 15 patients in both groups, respectively (P < 0.05). No postoperative infection or immune rejection occurred in either group during the follow-up. Comparing with the interrupted suture, using the continuous suture in femtosecond laser-assisted lamellar keratoplasty for keratoconus markedly limited the looseness of sutures with lesser corneal astigmatism and better visual quality postoperative.
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Funding
This study was supported by the National Natural Science Foundation of China (81570821, 81870639), the Key Project of the National Natural Science Foundation of China (81530027), Taishan Scholar Program (20150215, 201812150), and the Innovation Project of Shandong Academy of Medical Sciences. The funding organization had no role in the design or conduct of this research.
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All authors contributed to the study conception and design. Material preparation and data collection were performed by Yanni Jia; the data analyses were performed by Yanni Jia, Xiaolin Qi, and Ting Zhang. The first draft of the manuscript was written by Yanni Jia and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Jia, Y., Qi, X., Zhang, T. et al. Clinical outcomes of double continuous suture in femtosecond laser-assisted lamellar keratoplasty for keratoconus. Lasers Med Sci 36, 951–956 (2021). https://doi.org/10.1007/s10103-020-03114-y
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DOI: https://doi.org/10.1007/s10103-020-03114-y