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Heterogeneity in practices to reduce the risk of transmission of Clostridioides difficile in healthcare settings: a survey of ESCMID Study Group for Clostridioides difficile (ESGCD) members

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Abstract

Clostridioides difficile is a leading cause of healthcare-associated infections. The main objective was to assess the current landscape of CDI infection prevention and control (IPC) practices. An anonymous survey of IPC practices for CDI was conducted between July 25 and October 31, 2022. Precautions for symptomatic patients were applicable for 75.9% and were discontinued 48 h minimum after the resolution of diarrhea for 40.7% of respondents. Daily cleaning of CDI patients’ rooms was reported by 23 (42.6%). There was unexpected heterogeneity in IPC practices regarding the hospital management of CDI.

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Acknowledgements

The authors would like to acknowledge Patrick Kudyba, ESCMID for the survey diffusion.

Author information

Authors and Affiliations

  1. Infection Control Unit, Hôpital Edouard Herriot, Hospices Civils de Lyon (HCL), Lyon, France

    Nagham Léa Khanafer & Philippe Vanhems

  2. PHE3ID team, Centre International de Recherche en Infectiologie, Inserm U1111, CNRS UMR5308, ENS de Lyon, Lyon 1 University, Lyon, France

    Nagham Léa Khanafer & Philippe Vanhems

  3. European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Clostridioides difficile – ESGCD, Basel, Switzerland

    Nagham Léa Khanafer, Fidelma Fitzpatrick, Frédéric Barbut, Marcela Krutova, Kerrie Davies & Benoit Guery

  4. Department of Microbiology, Beaumont Hospital, Dublin, Ireland

    Fidelma Fitzpatrick

  5. Department of Clinical Microbiology, The Royal College of Surgeons in Ireland (RCSI) University of Medicine and Health Sciences, Dublin, Ireland

    Fidelma Fitzpatrick

  6. Infection Control Unit, Assistance Publique - Hôpitaux de Paris, Paris, France

    Frédéric Barbut

  7. National reference Laboratory for Clostridioides difficile, Paris, France

    Frédéric Barbut

  8. 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

    Marcela Krutova

  9. Healthcare Associated Infections Research Group, Leeds Teaching Hospitals, Leeds, UK

    Kerrie Davies

  10. Service of Infectious Diseases, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

    Benoit Guery

Authors
  1. Nagham Léa Khanafer
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  2. Fidelma Fitzpatrick
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  3. Frédéric Barbut
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  4. Marcela Krutova
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  5. Kerrie Davies
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  6. Benoit Guery
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  7. Philippe Vanhems
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Contributions

Conceptualization and statistical analysis: NK. Writing—original draft: NK. Writing—review and editing (alphabetic order): FB, KD, FF, BG, MK, and PV.

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Correspondence to Nagham Léa Khanafer.

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Conflict of interest

NK received scientific grants and/or consultation fees from Abbott, Astellas, BioMérieux, FINOVI, Sanofi Pasteur, and Tillotts Pharma; FF has received research grant support and been a recipient of a consultancy fee from Tillots Pharma; FB is an advisory board member for and/or has received scientific grants from Abbott, Astellas, BioMérieux, Cepheid, Cubist, Da Volterra, Danone, EliTech, Merck, Pfizer, Quidel, Sanofi Pasteur, Summit, and Tillotts Pharma; MK has no conflicts of interests; KD has received honorarium from Tillots Pharma and scientific grants from Alere, Cepheid, BioMérieux, and Techlab Ltd; BG is an advisory board member for and/or has received scientific grants from Pfizer and Tillots Pharma and PV received consulting grants from MSD, BD, Pfizer, and Tillots Pharma.

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Khanafer, N.L., Fitzpatrick, F., Barbut, F. et al. Heterogeneity in practices to reduce the risk of transmission of Clostridioides difficile in healthcare settings: a survey of ESCMID Study Group for Clostridioides difficile (ESGCD) members. Eur J Clin Microbiol Infect Dis 43, 785–789 (2024). https://doi.org/10.1007/s10096-024-04767-1

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  • DOI: https://doi.org/10.1007/s10096-024-04767-1

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