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Peripapillary vascular density in resolved non-arteritic anterior ischemic optic neuropathy: colocalization between structural and vascular parameters

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Abstract

Introduction/aims

Non-arteritic anterior ischemic optic neuropathy (NAION) is an acute infarction of the prelaminar anterior optic disc, resulting from the occlusion of posterior ciliary arteries. Here, we evaluated the correlation between structural and vascular features in a case of resolved NAION.

Methods

Observational case report.

Results

A 50-year-old male patient was referred at an Eye clinic due to an altitudinal visual field defect in the left eye, occurred 9 months before. Fundus examination was unremarkable, while structural SD-OCT reveals retinal nerve fiber layer (RNFL), ganglion cell complex (GCC) thinning associated with reduction of peripapillary vascular density at OCT Angiography.

Discussion

We found a precise spatial correlation among RNFL and GCC thinning, peripapillary vascular reduction and visual field defects. This case demonstrates that OCTA represents a new, valid and non-invasive imaging technique in the diagnosis and follow-up of NAION, even after the resolution of the acute phase, in the absence of clinical signs at fundus examination.

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Authors and Affiliations

  1. Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy

    Mariapaola Giordano, Daniela Montorio, Marina Concilio & Vincenzo Brescia Morra

  2. Department of Public Health, University of Naples Federico II, Via S. Pansini 5, 80133, Naples, Italy

    Gilda Cennamo

Authors
  1. Mariapaola Giordano
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  2. Daniela Montorio
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  3. Marina Concilio
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  4. Vincenzo Brescia Morra
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  5. Gilda Cennamo
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Corresponding author

Correspondence to Gilda Cennamo.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Giordano, M., Montorio, D., Concilio, M. et al. Peripapillary vascular density in resolved non-arteritic anterior ischemic optic neuropathy: colocalization between structural and vascular parameters. Neurol Sci 42, 4723–4725 (2021). https://doi.org/10.1007/s10072-021-05378-w

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  • DOI: https://doi.org/10.1007/s10072-021-05378-w

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