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Ganglioneuroblastoma in children

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Abstract

Introduction

Neuroblastoma ranks third among pediatric malignancies.

Case report

The case of a 3-year-old child is presented, who suddenly had frequent, unproductive, emetic cough; fever; and weight loss. Lung X-ray showed an opacity situated in the posterior superior mediastinum. Thoracic ultrasound revealed a slightly inhomogeneous, hypoechoic mass located in the posterior superior mediastinum. Computed tomography evidenced a tumor mass with homogeneous appearance in the costo-vertebral groove. Histological examination confirmed the diagnosis of ganglioneuroblastoma.

Conclusion

Although history and clinical examination provided few elements, diagnosis was made based on imaging and histopathological examination.

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Author notes

  1. Ioana Badiu Tișa, Gabriel Samașca, Cornel Aldea, Iulia Lupan, Dorin Farcau and Peter Makovicky contributed equally to this work.

Authors and Affiliations

  1. Clinic of Pediatrics III, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

    Ioana Badiu Tișa & Dorin Farcau

  2. Clinical Emergency Pediatric Hospital, Cluj-Napoca, Romania

    Gabriel Samașca & Cornel Aldea

  3. Clinic of Pediatrics II, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

    Gabriel Samașca & Cornel Aldea

  4. Babes Bolyai University, Cluj-Napoca, Romania

    Iulia Lupan

  5. Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the AS CR, v. v. i, Prague, Vestec, Czech Republic

    Peter Makovicky

Authors
  1. Ioana Badiu Tișa
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  2. Gabriel Samașca
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  5. Dorin Farcau
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Corresponding author

Correspondence to Gabriel Samașca.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Badiu Tișa, I., Samașca, G., Aldea, C. et al. Ganglioneuroblastoma in children. Neurol Sci 40, 1985–1989 (2019). https://doi.org/10.1007/s10072-019-03932-1

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