Data availability
Not applicable.
References
Schreiber K, Sciascia S, de Groot PG, et al. (2018) Antiphospholipid syndrome [published correction appears in Nat Rev Dis Primers. 2018 Jan 25;4:18005]. Nat Rev Dis Primers 4:17103. Published 2018 Jan 11. https://doi.org/10.1038/nrdp.2017.103
Devreese KMJ, de Groot PG, de Laat B et al (2020) Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis: update of the guidelines for lupus anticoagulant detection and interpretation. J Thromb Haemost 18(11):2828–2839. https://doi.org/10.1111/jth.15047
Vandevelde A, Devreese KMJ (2022) Laboratory diagnosis of antiphospholipid syndrome: insights and hindrances. J Clin Med. 11(8):2164. Published 2022 Apr 13. https://doi.org/10.3390/jcm11082164
Pengo V, Tripodi A, Reber G et al (2009) Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis. Update of the guidelines for lupus anticoagulant detection. Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibody of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis. J Thromb Haemost. 7(10):1737–1740. https://doi.org/10.1111/j.1538-7836.2009.03555.x Epub 2009 Jul 17
Devreese KM (2014) Antiphospholipid antibody testing and standardization. Int J Lab Hematol 36(3):352–363. https://doi.org/10.1111/ijlh.12234
Ong J, Bennett A (2022) A review of laboratory considerations in thrombophilia testing. Pathology 54(7):835–841. https://doi.org/10.1016/j.pathol.2022.09.001
Devreese KM, Verfaillie CJ, De Bisschop F, Delanghe JR (2015) Interference of C-reactive protein with clotting times. Clin. Chem. Lab. Med. 53:e141–e145. https://doi.org/10.1515/cclm-2014-0906
Schouwers SM, Delanghe JR, Devreese KM (2010) Lupus anticoagulant (LAC) testing in patients with inflammatory status: does C-reactive protein interfere with LAC test results? Thromb Res. 125(1):102–104. https://doi.org/10.1016/j.thromres.2009.09.001 Epub 2009 Sep 25
Vad S, Lakos G, Kiss E, Sipka S, Csorba R, Poka R (2003) Antiphospholipid antibodies in young women with and without oral contraceptive use. Blood Coagul Fibrinolysis. 14(1):57–60. https://doi.org/10.1097/00001721-200301000-00010
Ulcova-Gallova Z, Bibkova K, Micanova Z, Losan P, Babcova K (2015) Possible effect of extended use of hormonal contraception on increased levels of antiphospholipid antibodies in infertile women. Geburtshilfe Frauenheilkd. 75(3):251–254. https://doi.org/10.1055/s-0035-1545869
Ali H, Buechler CR, Sanaullah O, Lucas A, Lohr KL (2023) Iatrogenic ANA: an emerging source of expensive diagnostic confusion. Lupus 32(2):299–300. https://doi.org/10.1177/09612033221144600
Acknowledgements
None.
Funding
None.
Author information
Authors and Affiliations
Contributions
HA: writing—original draft, review and editing
CRB: writing—original draft, review and editing
OS: writing—review and editing
PP: writing—review and editing; supervision
Corresponding author
Ethics declarations
Ethics approval
Not applicable.
Disclosures
None.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Ali, H., Buechler, C.R., Sanaullah, O. et al. Pitfalls in antiphospholipid antibody testing: specifically interference from anticoagulation. Clin Rheumatol 43, 821–823 (2024). https://doi.org/10.1007/s10067-023-06813-3
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10067-023-06813-3