Skip to main content
Log in

Mitochondrial DNA haplogroups and amyotrophic lateral sclerosis

  • Letters to the Editors
  • Published:
Neurogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Swerdlow RH, Parks JK, Cassarino DS, Trimmer PA, Miller SW, Maguire DJ, Sheehan JP, Maguire RS, Pattee G, Juel VC, Phillips LH, Tuttle JB, Bennett JP Jr, Davis RE, Parker WD Jr (1998) Mitochondria in sporadic amyotrophic lateral sclerosis. Exp Neurol 153:135–142

    Article  PubMed  CAS  Google Scholar 

  2. Gajewski CD, Lin MT, Cudkowicz ME, Beal MF, Manfredi G (2003) Mitochondrial DNA from platelets of sporadic ALS patients restores normal respiratory functions in rho(0) cells. Exp Neurol 179:229–235

    Article  PubMed  CAS  Google Scholar 

  3. Mancuso M, Conforti FL, Rocchi A, Tessitore A, Muglia M, Tedeschi G, Panza D, Monsurro M, Sola P, Mandrioli J, Choub A, DelCorona A, Manca ML, Mazzei R, Sprovieri T, Filosto M, Salviati A, Valentino P, Bono F, Caracciolo M, Simone IL, La Bella V, Majorana G, Siciliano G, Murri L, Quattrone A (2004) Could mitochondrial haplogroups play a role in sporadic amyotrophic lateral sclerosis? Neurosci Lett 371:158–162

    Article  PubMed  CAS  Google Scholar 

  4. van der Walt JM, Nicodemus KK, Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH Jr, Goetz CG, Small GW, Mastaglia F, Stajich JM, McLaurin AC, Middleton LT, Scott BL, Schmechel DE, Pericak-Vance MA, Vance JM (2003) Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. Am J Hum Genet 72:804–811

    Article  PubMed  Google Scholar 

  5. Ghezzi D, Marelli C, Achilli A, Goldwurm S, Pezzoli G, Barone P, Pellecchia MT, Stanzione P, Brusa L, Bentivoglio AR, Bonuccelli U, Petrozzi L, Abbruzzese G, Marchese R, Cortelli P, Grimaldi D, Martinelli P, Ferrarese C, Garavaglia B, Sangiorgi S, Carelli V, Torroni A, Albanese A, Zeviani M (2005) Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson’s disease in Italians. Eur J Hum Genet 13:748–752

    Article  PubMed  CAS  Google Scholar 

  6. Pyle A, Foltynie T, Tiangyou W, Lambert C, Keers SM, Allcock LM, Davison J, Lewis SJ, Perry RH, Barker R, Burn DJ, Chinnery PF (2005) Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD. Ann Neurol 57:564–567

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

PFC is a Wellcome Trust Senior Fellow in Clinical Science. PJS is supported by the Wellcome Trust and the MND Association. We acknowledge the use of DNA from the British 1958 Birth Cohort collection funded by the Medical Research Council grant GR0000934 and the Wellcome Trust Grant 068545/Z/02.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Patrick F. Chinnery.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chinnery, P.F., Mowbray, C., Elliot, H. et al. Mitochondrial DNA haplogroups and amyotrophic lateral sclerosis. Neurogenetics 8, 65–67 (2007). https://doi.org/10.1007/s10048-006-0066-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10048-006-0066-9

Keywords

Navigation