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Recurrent rhabdoid meningioma with lymph node, pulmonary and bone metastases: a diagnostic and therapeutic challenge

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Abstract

Rhabdoid meningioma is a rare meningioma variant, classified as WHO grade III. Although this tumor is known for its aggressive behavior and poor prognosis, extracranial metastasis is rare. We report the rare case of a 31-year-old patient with rhabdoid meningioma which recurred several times despite gross total resection, radiation therapy, and gamma knife radiosurgery, and the last recurrence was associated with metastases to lungs, lymph node and bone. The patient showed no response to paclitaxel–carboplatin, or vincristine–cyclophosphamide–adriamycin chemotherapy, and succumbed to the disease. Metastases from rhabdoid meningioma prove to be a diagnostic challenge, and treatment for metastatic meningiomas is not optimized, thus necessitating documentation and interdisciplinary consensus on management protocols.

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Authors and Affiliations

  1. Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India

    Aanchal Kakkar, Vaishali Suri, Chitra Sarkar & Mehar Chand Sharma

  2. Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, 110029, India

    Saphalta Baghmar & Vinod Raina

  3. Department of Neuroradiology, All India Institute of Medical Sciences, New Delhi, 110029, India

    Ajay Garg

Authors
  1. Aanchal Kakkar
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  2. Saphalta Baghmar
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  3. Ajay Garg
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  4. Vaishali Suri
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  5. Vinod Raina
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  6. Chitra Sarkar
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  7. Mehar Chand Sharma
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Correspondence to Mehar Chand Sharma.

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Kakkar, A., Baghmar, S., Garg, A. et al. Recurrent rhabdoid meningioma with lymph node, pulmonary and bone metastases: a diagnostic and therapeutic challenge. Brain Tumor Pathol 33, 228–233 (2016). https://doi.org/10.1007/s10014-016-0250-z

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  • DOI: https://doi.org/10.1007/s10014-016-0250-z

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