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Evaluation of the efficacy of laser-assisted flapless corticotomy in accelerating canine retraction: a split-mouth randomized controlled clinical trial

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Abstract

Objective

To evaluate the efficacy of laser-assisted flapless corticotomy in the acceleration of canine retraction compared with the conventional technique and to evaluate patients’ pain and discomfort levels after corticotomy.

Materials and methods

A single-center randomized controlled trial was conducted on 18 class II division 1 patients (7 males, 11 females; age range: 16 to 24 years) who required the first-upper-premolar extraction followed by canine retraction. A split-mouth design was used in which the Er:YAG laser-assisted flapless corticotomy was randomly allocated to one side, whereas the other side served as the control side. The primary outcome measure was the canine retraction rate which was assessed immediately after laser application, 1, 2, 4, 8, and 12 weeks after laser application. Also, the levels of pain and discomfort during the first week following laser application were assessed. Paired t-tests or Wilcoxon matched-pairs signed-rank tests were used to detect significant differences.

Results

All of the selected eighteen patients entered the statistical analysis stage. Significant differences were observed (P < 0.001) in canine retraction rates between the experimental and control sides at the baseline to 1st-week, 1st- to 2nd-week, 2nd- to 4th-week, and 4th- to 8th-week intervals. No significant difference was found between the two sides at the 8th- to 12th-week interval. A significant reduction was seen in the mean score of pain during eating at all assessment times when compared to the baseline data (P = 0.002 at day 2, P < 0.001 at days 5 and 7).

Conclusion

Er:YAG laser-assisted flapless corticotomy appears to be an effective treatment method for accelerating canine retraction and was accompanied by a mild degree of pain and discomfort.

Trial registration

ClinicalTrials.gov (No.: NCT04316403), retrospectively registered on the 20th of March 2020. URL: https://clinicaltrials.gov/ct2/show/NCT04316403

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Data availability

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Abbreviations

RAP:

Regional acceleratory phenomenon

ICCs:

Intraclass correlation coefficients

RCT:

Randomized control trial

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Funding

This study was funded by the University of Hama Postgraduate Research Budget (Reference number: UHDS-6057_2015DENRB).

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Authors and Affiliations

Authors

Contributions

STJ treated the recruited patients, did the surgical intervention, analyzed the collected data, interpreted the results, and wrote the first drafts of this manuscript. RAA supervised this trial, planned the study design, and helped in writing up the manuscript. MYH helped in the statistical analysis, in the interpretation of the results, and in the writing up of this manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Mohammad Y. Hajeer.

Ethics declarations

Ethics approval and consent to participate

Ethical approval was obtained from the Research Ethics Committee of the University of Hama Dental School, Syria (Approval no. UHDS-3101_2015PG).

Consent for publication

Not applicable.

Competing interests

The authors declare no competing interests.

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Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary Figure 1

Bland-Altman analysis for the repeated measures in the study (experimental Side) (JPG 237 kb)

Supplementary Figure 2

Bland-Altman analysis for the repeated measures in the study (control side) (JPG 216 kb)

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Jaber, S.T., Al-Sabbagh, R. & Hajeer, M.Y. Evaluation of the efficacy of laser-assisted flapless corticotomy in accelerating canine retraction: a split-mouth randomized controlled clinical trial. Oral Maxillofac Surg 26, 81–89 (2022). https://doi.org/10.1007/s10006-021-00963-x

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  • DOI: https://doi.org/10.1007/s10006-021-00963-x

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