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Eruption sequestrum: an inflamed odontogenic hamartoma

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Abstract

Eruption sequestrum (ES) is a single or even multiple, small whitish calcified masses found within the soft tissue of the opercula overlying the crown of erupting permanent molars of children. We herein report a well-documented case of ES, offering a review of published cases in the English literature. An otherwise healthy 6-year-old girl was seen for routine dental examination. A fragment of hard whitish tissue was observed in the gingiva overlying the erupting lower first permanent molar, which showed radiographic appearance of a faint round radiopacity above and separated from the occlusal surface of the related tooth. The patient was submitted to an excisional biopsy, and gross examination showed a hardened whitish fragment surrounded by gingival mucosa. Microscopic examination revealed odontogenic epithelium in association with chronic inflammatory infiltrate and small blood vessels in the connective tissue. Small concentric basophilic calcifications, round osteodentin, and pulp-like structures were also observed. The microscopic evaluation of additional cases of ES may improve the understanding of this uncommon inflamed odontogenic hamartoma.

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Authors and Affiliations

Authors

Contributions

ALOCR and TCAB contributed to the clinical and microscopic analyses of the case studied and review of the literature. KTB, ACA, MA, BABA, PAV, and MJR contributed to the study design, final data analyses, and manuscript writing and editing. All authors gave final approval and agreed to be accountable for all aspects of the work.

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Correspondence to Mário José Romañach.

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The authors declare that they have no conflicts of interest.

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This article does not contain any studies with animals performed by any of the authors. All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Roza, A.L.O.C., de Abreu Brandi, T.C., Bezerra, K.T. et al. Eruption sequestrum: an inflamed odontogenic hamartoma. Oral Maxillofac Surg 24, 363–368 (2020). https://doi.org/10.1007/s10006-020-00865-4

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