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Toothpaste factors related to dentine tubule occlusion and dentine protection against erosion and abrasion

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Abstract

Objectives

To investigate the effect of toothpastes on dentine surface loss and tubule occlusion, and the association of toothpaste-related factors to each of the outcomes.

Materials and methods

One hundred and sixty human dentine specimens were randomly distributed into 10 groups, according to different toothpastes. The specimens were submitted to artificial saliva (60 min), citric acid (3 min), and brushing abrasion (25 s; totalizing 2 min in toothpaste slurries). This was repeated five times and two outcome variables were analyzed: dentine surface loss (dSL; μm) and tubule occlusion by measurement of the total area of open tubules (Area-OT; μm2). Data were analyzed with Kruskal-Wallis and Mann-Whitney tests (α = 0.05); bivariate and multivariate regressions were used to model the association of the chemical (pH, concentration of F−, Ca2+, and PO43− and presence of Sn2+) and physical (% weight of solid particles, particle size, and wettability) factors of the toothpastes to both outcome variables.

Results

Toothpastes caused different degrees of dSL and did not differ in Area-OT. All chemical and physical factors, except the presence of Sn2+, were associated with dSL (p < 0.001). Area-OT was associated only with the presence of Sn2+ (p = 0.033).

Conclusion

Greater dSL was associated with lower pH, lower concentration of F−, higher concentration of Ca2+ and PO43−, greater % weight of solid particles, smaller particle size, and lesser wettability, whereas tubule occlusion was associated with the presence of Sn2+.

Clinical relevance

Depending on their chemical and physical composition, toothpastes will cause different degrees of dentine tubule occlusion and dentine surface loss. This could, in turn, modulate dentine hypersensitivity.

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Acknowledgments

Department of Restorative, Preventive and Pediatric Dentistry–University of Bern; São Paulo Research Foundation (FAPESP; process number 2015/23620-0); Swiss Government Excellence Scholarships for Foreign Scholars and Artists (ESKAS Scholarship; 2018.0515).

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Authors and Affiliations

  1. Department of Restorative, Preventive and Pediatric Dentistry, University of Bern, Freiburgstrasse 7, CH-3010, Bern, Switzerland

    Samira Helena João-Souza, Adrian Lussi, Tommy Baumann & Thiago Saads Carvalho

  2. Department of Restorative Dentistry, University of São Paulo, São Paulo, Brazil

    Samira Helena João-Souza, Leticia Oba Sakae, Ana Cecilia Corrêa Aranha & Tais Scaramucci

  3. Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN, USA

    Anderson Hara

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  1. Samira Helena João-Souza
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  2. Leticia Oba Sakae
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  4. Ana Cecilia Corrêa Aranha
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Correspondence to Samira Helena João-Souza.

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The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in this study were in accordance with the ethical standards of the local research committee (Kantonale Ethikkommission: KEK) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This study was granted exemption from requiring ethics approval, as detailed in the “Materials and methods” section.

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João-Souza, S.H., Sakae, L.O., Lussi, A. et al. Toothpaste factors related to dentine tubule occlusion and dentine protection against erosion and abrasion. Clin Oral Invest 24, 2051–2060 (2020). https://doi.org/10.1007/s00784-019-03069-7

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