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KAl(SO4)2 · 12H2O (alum) a reusable catalyst for the synthesis of some 4-substituted coumarins via Pechmann reaction under solvent-free conditions

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Abstract

A simple, efficient, and practical procedure for the Pechmann condensation using KAl(SO4)2 · 12H2O (alum) as a non-toxic, reusable, inexpensive, and easily available catalyst is described under solvent-free condition at 65°C. These improved reaction conditions allow the preparation of a wide variety of some new substituted coumarins in high yields (86–96%) and purity under mild reaction conditions. Compared to the classical Pechmann condensation, this new method consistently has the advantage of high yields.

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Authors and Affiliations

  1. Department of Chemistry, Shahid Beheshti University, Tehran, Iran

    Javad Azizian, Ali A. Mohammadi & Peiman Mirzaei

  2. Department of Chemistry, Islamic Azad University-Branch Saveh, Saveh, Iran

    Ilyar Bidar

Authors
  1. Javad Azizian
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  2. Ali A. Mohammadi
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  3. Ilyar Bidar
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  4. Peiman Mirzaei
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Corresponding author

Correspondence to Ali A. Mohammadi.

Additional information

Correspondence: Ali A. Mohammadi, Department of Chemistry, Shahid Beheshti University, P.O. Box 19839-4716, Tehran, Iran.

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Azizian, J., Mohammadi, A., Bidar, I. et al. KAl(SO4)2 · 12H2O (alum) a reusable catalyst for the synthesis of some 4-substituted coumarins via Pechmann reaction under solvent-free conditions. Monatsh Chem 139, 805–808 (2008). https://doi.org/10.1007/s00706-007-0833-9

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  • DOI: https://doi.org/10.1007/s00706-007-0833-9

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