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Characterization of the first bovine gammaherpesvirus 4 strain isolated from an aborted bovine fetus in Argentina

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Abstract

Bovine herpesvirus 4 (BoHV-4) is increasingly believed to be responsible for several disorders of the bovine reproductive tract. The first characterization of BoHV-4 in Argentina was from samples from an aborted fetus. Argentinean isolates are highly diverse and are phylogenetically grouped in three genotypes. In this study, we describe the isolation of BoHV-4 from a bovine fetus with a gestational age of 8 months and without macroscopic lesions. Genetic analyses revealed that the isolated strain belongs to genotype 2. This is the first report on the presence of infectious BoHV-4 in tissues from an aborted bovine fetus.

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Acknowledgements

This work was supported by Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT) through PICT 2011-0312 and PICT 2008-1421. Specialized Veterinary Diagnostic Service at INTA, Balcarce, Argentina and Instituto de Biotecnología, CICVyA, INTA, Argentina.

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Authors and Affiliations

  1. Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT), Godoy Cruz 2370, C1425FQD, Buenos Aires, Argentina

    Romeo Florencia

  2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Rivadavia 1917, C1033AAJ, Buenos Aires, Argentina

    Manrique Julieta, Perez Sandra, Marín Maia, González Altamiranda Erika, Spetter Maximiliano, Jones Leandro & Andrea E. Verna

  3. Laboratorio de Virología y Genética Molecular, Facultad de Ciencias Naturales y Ciencias de la Salud, Universidad Nacional de la Patagonia San Juan Bosco, Trelew, Chubut, Argentina

    Manrique Julieta & Jones Leandro

  4. Grupo de Sanidad Animal, Instituto Nacional de Tecnología Agropecuaria (INTA), 7620, Balcarce, Argentina

    Romeo Florencia, Louge Uriarte Enrique, Marín Maia, Cantón German, Maria R. Leunda, González Altamiranda Erika, Pereyra Susana, Spetter Maximiliano, Odeón Anselmo & Andrea E. Verna

  5. Facultad de Ciencias Veterinarias, Universidad Nacional del Centro de la Provincia de Buenos Aires (UNCPBA), Sede Tandil, Buenos Aires, Argentina

    Perez Sandra

Authors
  1. Romeo Florencia
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  2. Manrique Julieta
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  3. Perez Sandra
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  4. Louge Uriarte Enrique
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  5. Marín Maia
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  6. Cantón German
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  7. Maria R. Leunda
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  8. González Altamiranda Erika
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  9. Pereyra Susana
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  10. Spetter Maximiliano
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  11. Odeón Anselmo
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  12. Jones Leandro
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  13. Andrea E. Verna
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Corresponding author

Correspondence to Andrea E. Verna.

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Handling Editor: Zhongjie Shi.

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Florencia, R., Julieta, M., Sandra, P. et al. Characterization of the first bovine gammaherpesvirus 4 strain isolated from an aborted bovine fetus in Argentina. Arch Virol 165, 719–723 (2020). https://doi.org/10.1007/s00705-019-04507-3

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  • DOI: https://doi.org/10.1007/s00705-019-04507-3

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