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Complete genome sequence of the NVSL BoHV-1.1 Cooper reference strain

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Abstract

The only complete genome sequence available for bovine herpesvirus 1 (BoHV-1) is a composite sequence derived from four different BoHV-1.1 strains and one BoHV-1.2 strain. Such a chimeric genome sequence is problematic for molecular genetic studies on this virus. We report here the complete genome sequence for the BoHV-1.1 NVSL reference strain Cooper. Although similar to the published chimeric genome sequence, there are a number of nucleotide substitutions and deletions/insertions across the genome, many of which affect coding sequences.

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Acknowledgments

The research was supported by the Center for Veterinary Health Sciences and a grant from Novartis Animal Health, Greensboro, NC.

Conflict of interest

None of the authors have any personal or financial conflict of interest that would bias the results of this study.

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Authors and Affiliations

  1. Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, 250 McElroy Hall, Stillwater, OK, 74078, USA

    Jean M. d’Offay, Robert W. Fulton & R. Eberle

Authors
  1. Jean M. d’Offay
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  2. Robert W. Fulton
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  3. R. Eberle
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Corresponding author

Correspondence to Jean M. d’Offay.

Additional information

Nucleotide sequence data reported in GenBank under accession number JX898220.

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d’Offay, J.M., Fulton, R.W. & Eberle, R. Complete genome sequence of the NVSL BoHV-1.1 Cooper reference strain. Arch Virol 158, 1109–1113 (2013). https://doi.org/10.1007/s00705-012-1574-6

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  • DOI: https://doi.org/10.1007/s00705-012-1574-6

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