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Predominance of rotavirus G2P[4] and emergence of G12P[9] strains in Asunción, Paraguay, 2006–2007

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Abstract

Rotavirus is the most common cause of severe diarrhea in children worldwide. Monitoring the diversity of rotavirus strains is of great importance for current and future vaccination programs. To determine the diversity of rotavirus circulating in Asuncion, Paraguay, between 2006 and 2007, we carried out a molecular characterization of rotaviruses detected in children <5 years old and adults (>18 years old). We found that the most common circulating strain was G2P[4] (69/143), followed by G9P[8] (37/143). The temporal distribution of strains showed that, in children, G2P[4] was predominant in 2006, and that G2P[4] and G9P[8] were co-predominant in 2007, whereas in adults, G2P[4] was predominant in both years. Additionally, one G9P[6] and three G12P[9] strains were found in adult samples, making this the first report of these strains circulating in Paraguay. Sequence analysis of the G12P[9] strains suggests across-border migration of this strain within the southern cone of America.

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Acknowledgments

We thank Maria Victoria Gonzalez Eusevi for her critical reading and editing of the manuscript.

Conflict of interest statement

The authors have no conflicts of interest to declare.

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Author notes

  1. Gabriel I. Parra

    Present address: Laboratory of Infectious Diseases, NIAID, National Institute of Health, 9000 Rockville Pike, Bldg 50, Room 6316, Bethesda, MD, 20892, USA

  2. Victor H. Aquino

    Present address: Clinical, Toxicological and Bromatological Department, Faculty of Pharmaceutical Sciences of Ribeirão Preto, USP, Ribeirão Preto, Brazil

Authors and Affiliations

  1. Molecular Biology Department, IICS, National University of Asuncion, Río de la Plata y Lagerenza, 2511, Asunción, Paraguay

    Magaly Martínez, Alberto A. Amarilla, Maria E. Galeano, Norma Fariña, Graciela Russomando & Gabriel I. Parra

  2. Virology Research Center, Ribeirão Preto School of Medicine, USP, Av. Bandeirantes, Ribeirão Preto, SP, 3900, Brazil

    Alberto A. Amarilla & Victor H. Aquino

  3. Clinical Laboratory of San Roque Private Hospital, Asunción, Paraguay

    Norma Fariña

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  1. Magaly Martínez
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Corresponding author

Correspondence to Gabriel I. Parra.

Additional information

M. Martínez and G. I. Parra contributed equally to this work.

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Martínez, M., Amarilla, A.A., Galeano, M.E. et al. Predominance of rotavirus G2P[4] and emergence of G12P[9] strains in Asunción, Paraguay, 2006–2007. Arch Virol 155, 525–533 (2010). https://doi.org/10.1007/s00705-010-0617-0

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