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Deep brain stimulation and development of a high-grade glioma: incidental or causal association?

  • Case Report - Brain Tumors
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Abstract

We report the case of a patient in whom 8.8 years following the implantation of a bilateral deep brain stimulation (DBS) into the Vim, a high-grade glioma was diagnosed in close proximity to the two electrode leads. A possible relationship between the permanent DBS and the development of the brain tumour is discussed.

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References

  1. Amorim BO, Covolan L, Ferreira E, Brito JG, Nunes DP, de Morais DG, Obrega JN, Rodrigues AM, deAlmeida ACG, Hamani C (2015) Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats. J Neuroinflammation 12:162–167

    Article  PubMed  PubMed Central  Google Scholar 

  2. Calleja-Castillo JM, Luz de la Cruz-Aguilera D, Manjarrez J, Velasco-Velasquez MA, Morales-Espinoza G, Moreno-Aguilar J, Hernandez ME, Aguirre-Cruz L, Pavon L (2013) Chronic deep brain stimulation of the hypothalamic nucleus in wistar rats alters circulatory levels of corticosterone and proinflammatory cytokines. Clin Dev Immunol 2013:698634. doi:10.1155/2013/698634

    Article  PubMed  PubMed Central  Google Scholar 

  3. Kalakoti P, Murray RD, Pettersson-Segerlind J, Smeds H, Nanda A (2016) Cochlear implants in the etio-pathogenesis of glioblastoma—an interesting observation or an independent finding? Acta Neurochir (Wien). doi:10.1007/s00701-016-2718-3

  4. Rehman AA, Elmore KB, Mattei TA (2015) The effect of alternating electric fields in glioblastoma: current evidence on therapeutic mechanisms and clinical outcomes. Neurosurg Focus 38:E14–E24

    Article  PubMed  Google Scholar 

  5. Elwassif MM, Datta A, Rahman A, Bikson M (2012) Temperature control at DBS electrodes using heat sink: experimentally validated FEM model of DBS lead architechture. J Neural Eng 9(4):046009. doi: 10.1088/1741-2560/9/4/046009

  6. Rizzi M, De Benedictis A, Messina G, Cordella R, Marchesi D, Messina R, Penner F, Franzini A, Marras CE (2015) Comparative analysis of explanted DBS electrodes. Acta Neurochir (Wien) 157:2135–2141

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Authors and Affiliations

  1. Neurosurgery, Klinik Im Park, Seestrasse 220, 8027, Zurich, Switzerland

    Thomas Mindermann

  2. Neurosurgery, Hirslanden Klinik Aarau, Schänisweg, 5001 Aarau, Switzerland

    Aminadav Mendelowitsch

Authors
  1. Thomas Mindermann
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  2. Aminadav Mendelowitsch
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Correspondence to Thomas Mindermann.

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Mindermann, T., Mendelowitsch, A. Deep brain stimulation and development of a high-grade glioma: incidental or causal association?. Acta Neurochir 158, 915–917 (2016). https://doi.org/10.1007/s00701-016-2773-9

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  • DOI: https://doi.org/10.1007/s00701-016-2773-9

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