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Micro and nanoparticles in biosensing systems for food safety and environmental monitoring. An example of converging technologies

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Abstract

We report on the integration of micro and nanostructured materials in biosensing devices to obtain analytical nano-bio-systems with improved performance. The simplest case of electrochemical biosensing presented here is based on graphite microparticles to obtain a graphite-epoxy composite. The integration of the bioreceptor within the composite provides an analytical biosystem with improved performances for biosensing. The further addition of gold nanoparticles results in an analytical nano-bio-system which allows an improved strategy for the immobilization of the bioreceptor. And finally, the integration of magnetic beads to graphite-epoxy composite magneto electrodes provides further advantages in terms of separation of the analyte from complex matrix and enhanced biological reactions, resulting in analytical magneto-nano-bio-systems. The application of these systems mainly in food safety and environmental monitoring are reported. The benefits of the integration of these materials to obtain improved analytical systems are discussed and represent an example of converging technologies.

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Acknowledgements

Financial support from Ministry of Science and Innovation (MICINN, Madrid, Spain) (Projects BIO2007-63300 and PHB2008-0081-PC), are acknowledged.

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Authors and Affiliations

  1. Grup de Sensors i Biosensors, Departament de Química, Universitat Autónoma de Barcelona, Barcelona, Spain

    María Isabel Pividori & Salvador Alegret

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  1. María Isabel Pividori
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  2. Salvador Alegret
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Correspondence to Salvador Alegret.

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Pividori, M.I., Alegret, S. Micro and nanoparticles in biosensing systems for food safety and environmental monitoring. An example of converging technologies. Microchim Acta 170, 227–242 (2010). https://doi.org/10.1007/s00604-010-0347-8

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  • DOI: https://doi.org/10.1007/s00604-010-0347-8

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