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A marker of type VI collagen formation (PRO-C6) is associated with higher arterial stiffness in type 1 diabetes

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References

  1. Vlachopoulos C, Aznaouridis K, Stefanadis C (2010) Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 55(13):1318–1327

    Article  Google Scholar 

  2. Lacolley P, Regnault V, Segers P, Laurent S (2017) Vascular smooth muscle cells and arterial stiffening: relevance in development, aging, and disease. Physiol Rev 97(4):1555–1617

    Article  CAS  PubMed  Google Scholar 

  3. Sun S, Henriksen K, Karsdal MA et al (2015) Collagen type III and VI turnover in response to long-term immobilization. PLoS One 10(12):e0144525

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Rasmussen DGK, Hansen TW, von Scholten BJ et al (2018) Higher collagen VI formation is associated with all-cause mortality in patients with type 2 diabetes and microalbuminuria. Diabetes Care

  5. Theilade S, Lajer M, Persson F, Joergensen C, Rossing P (2013) Arterial stiffness is associated with cardiovascular, renal, retinal, and autonomic disease in type 1 diabetes. Diabetes Care 36(3):715–721

    Article  PubMed  PubMed Central  Google Scholar 

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Author contributions

MF, TWH, PR, DGKR and FG conceived and designed the letter. MF and TWH drafted the manuscript. PR, DGKR and FG critically revised the manuscript. All authors read and approved the final manuscript.

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Authors and Affiliations

  1. Steno Diabetes Center Copenhagen, Copenhagen, Denmark

    Marie Frimodt-Møller, Tine W. Hansen, Simone Theilade & Peter Rossing

  2. Nordic Bioscience, Herlev, Denmark

    Daniel G. K. Rasmussen, Signe H. Nielsen, Morten A. Karsdal & Federica Genovese

  3. University of Copenhagen, Copenhagen, Denmark

    Peter Rossing

Authors
  1. Marie Frimodt-Møller
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  2. Tine W. Hansen
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  3. Daniel G. K. Rasmussen
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  4. Simone Theilade
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  5. Signe H. Nielsen
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  6. Morten A. Karsdal
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  7. Federica Genovese
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  8. Peter Rossing
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Corresponding author

Correspondence to Marie Frimodt-Møller.

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Conflict of interest

DGKR, SHN, MAK, and FG are full-time employees of Nordic Bioscience. Nordic Bioscience is a privately owned, small- to medium-sized enterprise partly focused on the development of biomarkers. None of the authors received fees, bonuses, or other benefits for the work described in the article. MAK and FG hold stocks in Nordic Bioscience. The patent for the ELISAs used to measure PRO-C6 and C3M levels is owned by Nordic Bioscience. The funder provided support in the form of salaries for DGKR, SHN, MAK, and FG but did not play any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. There are no conflicts of interest to disclose for PR, ST, TWH or MF.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Frimodt-Møller, M., Hansen, T.W., Rasmussen, D.G.K. et al. A marker of type VI collagen formation (PRO-C6) is associated with higher arterial stiffness in type 1 diabetes. Acta Diabetol 56, 711–712 (2019). https://doi.org/10.1007/s00592-019-01306-9

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  • DOI: https://doi.org/10.1007/s00592-019-01306-9

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