Abstract
Purpose
L5 pedicle subtraction osteotomy (PSO) is a demanding technique; thus, PSOs are usually performed at the L3/L4 level to correct the lack of lumbar lordosis. Mid- to long-term improvements in clinical outcomes after L5 PSO are unknown. We aimed to determine the efficacy and safety of L5 PSO for rigid kyphosis deformities.
Methods
We retrospectively reviewed the records of 57 patients with a rigid kyphosis deformity (mean age: 68 years) who underwent extensive corrective surgery incorporating PSO with a > 2-year follow-up. Radiographic parameters, postoperative complication rates, and the Oswestry Disability Index (ODI) scores were compared in the L5, L4, and L1-3 PSO groups preoperatively and at 1, 2, and 5 years postoperatively.
Results
There were 12, 25, and 20 patients in the L5, L4, and L1-3 PSO groups, respectively. Significant between-group differences were found in preoperative L4–S1 lordosis (L5:L4:L1-3 PSO groups = − 8.9°:8.9°:16.2°, P < 0.001). The surgeries improved the postoperative spinopelvic alignment (similar in all groups). There was no significant between-group difference in the postoperative complication rate; no irreversible complications occurred. In the L5 PSO group, there was one case of a common iliac vein injury. The ODI scores improved postoperatively in all groups; this was maintained for 5 years postoperatively.
Conclusion
L5 PSO for L4-5/L5 kyphosis deformities resulted in adequate correction and ODI improvement, which were maintained up to 5 years postoperatively. The surgical invasiveness, complication rates, and long-term prognosis associated with L5 PSO were similar to those of PSOs performed at other levels.
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Availability of data and material
The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.
References
Funao H, Kebaish FN, Skolasky RL, Kebaish KM (2020) Clinical results and functional outcomes after three-column osteotomy at L5 or the sacrum in adult spinal deformity. Eur Spine J. https://doi.org/10.1007/s00586-019-06255-z
Alzakri A, Boissiere L, Cawley DT, Bourghli A, Pointillart V, Gille O, Vital JM, Obeid I (2018) L5 pedicle subtraction osteotomy: indication, surgical technique and specificities. Eur Spine J 27:644–651. https://doi.org/10.1007/s00586-017-5403-1
Bridwell KH (2006) Decision making regarding Smith-Petersen versus pedicle subtraction osteotomy versus vertebral column resection for spinal deformity. Spine 31:S171–178. https://doi.org/10.1097/01.brs.0000231963.72810.38
Kim KT, Lee SH, Suk KS, Lee JH, Jeong BO (2012) Outcome of pedicle subtraction osteotomies for fixed sagittal imbalance of multiple etiologies: a retrospective review of 140 patients. Spine 37:1667–1675. https://doi.org/10.1097/BRS.0b013e3182552fd0
Bridwell KH, Lewis SJ, Rinella A, Lenke LG, Baldus C, Blanke K (2004) Pedicle subtraction osteotomy for the treatment of fixed sagittal imbalance. Surg Tech J Bone Joint Surg Am 86:44–50. https://doi.org/10.2106/00004623-200403001-00007
Kim HJ, Yi JM, Cho HG, Chang BS, Lee CK, Kim JH, Yeom JS (2014) Comparative study of the treatment outcomes of osteoporotic compression fractures without neurologic injury using a rigid brace, a soft brace, and no brace: a prospective randomized controlled non-inferiority trial. J Bone Joint Surg Am 96:1959–1966. https://doi.org/10.2106/JBJS.N.00187
Hasegawa T, Ushirozako H, Yamato Y, Togawa D, Yoshida G, Kobayashi S, Yasuda T, Banno T, Arima H, Oe S, Yamada T, Ide K, Watanabe Y, Matsuyama Y (2020) Impact of adult spinal deformity corrective surgery in patients with the symptoms of gastroesophageal reflux disease: a 5-year follow-up report. Eur Spine J. https://doi.org/10.1007/s00586-020-06300-2
Fairbank JC, Pynsent PB (2000) The Oswestry Disability Index. Spine 25:2940–2952. https://doi.org/10.1097/00007632-200011150-00017(discussion 2952)
Bridwell KH, Cats-Baril W, Harrast J, Berven S, Glassman S, Farcy JP, Horton WC, Lenke LG, Baldus C, Radake T (2005) The validity of the SRS-22 instrument in an adult spinal deformity population compared with the Oswestry and SF-12: a study of response distribution, concurrent validity, internal consistency, and reliability. Spine 30:455–461. https://doi.org/10.1097/01.brs.0000153393.82368.6b
Banno T, Hasegawa T, Yamato Y, Kobayashi S, Togawa D, Oe S, Mihara Y, Matsuyama Y (2017) Prevalence and risk factors of iliac screw loosening after adult spinal deformity surgery. Spine 42:E1024–E1030. https://doi.org/10.1097/BRS.0000000000002047
Diebo B, Liu S, Lafage V, Schwab F (2014) Osteotomies in the treatment of spinal deformities: indications, classification, and surgical planning. Eur J Orthop Surg Traumatol 24(Suppl 1):S11–20. https://doi.org/10.1007/s00590-014-1471-7
Yoshida G, Ushirozako H, Kobayashi S, Hasegawa T, Yamato Y, Banno T, Oe S, Arima H, Mihara Y, Yasuda T, Togawa D, Matsuyama Y (2019) Intraoperative neuromonitoring during adult spinal deformity surgery: alert-positive cases for various surgical procedures. Spine Deform 7:132–140. https://doi.org/10.1016/j.jspd.2018.05.015
Ushirozako H, Yoshida G, Kobayashi S, Hasegawa T, Yamato Y, Yasuda T, Banno T, Arima H, Oe S, Mihara Y, Togawa D, Matsuyama Y (2018) Transcranial motor evoked potential monitoring for the detection of nerve root injury during adult spinal deformity surgery. Asian Spine J 12:639–647. https://doi.org/10.31616/asj.2018.12.4.639
Boissiere L, Bourghli A, Vital JM, Gille O, Obeid I (2013) The lumbar lordosis index: a new ratio to detect spinal malalignment with a therapeutic impact for sagittal balance correction decisions in adult scoliosis surgery. Eur Spine J 22:1339–1345. https://doi.org/10.1007/s00586-013-2711-y
Roussouly P, Gollogly S, Berthonnaud E, Dimnet J (2005) Classification of the normal variation in the sagittal alignment of the human lumbar spine and pelvis in the standing position. Spine 30:346–353. https://doi.org/10.1097/01.brs.0000152379.54463.65
Obeid I, Boissiere L, Vital JM, Bourghli A (2015) Osteotomy of the spine for multifocal deformities. Eur Spine J 24(Suppl 1):S83–92. https://doi.org/10.1007/s00586-014-3660-9
Barrey C, Perrin G, Michel F, Vital JM, Obeid I (2014) Pedicle subtraction osteotomy in the lumbar spine: indications, technical aspects, results and complications. Eur J Orthop Surg Traumatol 24(Suppl 1):S21–30. https://doi.org/10.1007/s00590-014-1470-8
Yoshida G, Hasegawa T, Yamato Y, Kobayashi S, Oe S, Banno T, Mihara Y, Arima H, Ushirozako H, Yasuda T, Togawa D, Matsuyama Y (2018) Predicting perioperative complications in adult spinal deformity surgery using a simple sliding scale. Spine 43:562–570. https://doi.org/10.1097/BRS.0000000000002411
Yamato Y, Hasegawa T, Kobayashi S, Yasuda T, Togawa D, Yoshida G, Banno T, Oe S, Mihara Y, Matsuyama Y (2018) Treatment strategy for rod fractures following corrective fusion surgery in adult spinal deformity depends on symptoms and local alignment change. J Neurosurg Spine 29:59–67. https://doi.org/10.3171/2017.9.SPINE17525
Yamato Y, Hasegawa T, Togawa D, Yoshida G, Banno T, Arima H, Oe S, Mihara Y, Ushirozako H, Yasuda T, Matsuyama Y (2020) Long additional rod constructs can reduce the incidence of rod fractures following 3-column osteotomy with pelvic fixation in short term. Spine Deform. https://doi.org/10.1007/s43390-020-00071-y
Maruo K, Ha Y, Inoue S, Samuel S, Okada E, Hu SS, Deviren V, Burch S, William S, Ames CP, Mummaneni PV, Chou D, Berven SH (2013) Predictive factors for proximal junctional kyphosis in long fusions to the sacrum in adult spinal deformity. Spine 38:E1469–1476. https://doi.org/10.1097/BRS.0b013e3182a51d43
Nguyen JH, Buell TJ, Wang TR, Mullin JP, Mazur MD, Garces J, Taylor DG, Yen CP, Shaffrey CI, Smith JS (2019) Low rates of complications after spinopelvic fixation with iliac screws in 260 adult patients with a minimum 2-year follow-up. J Neurosurg Spine. https://doi.org/10.3171/2018.9.SPINE18239
Yagi M, Rahm M, Gaines R, Maziad A, Ross T, Kim HJ, Kebaish K, Boachie-Adjei O, Complex Spine Study G (2014) Characterization and surgical outcomes of proximal junctional failure in surgically treated patients with adult spinal deformity. Spine 39:E607–614. https://doi.org/10.1097/BRS.0000000000000266
Oe S, Togawa D, Hasegawa T, Yamato Y, Yoshida G, Kobayashi S, Yasuda T, Banno T, Arima H, Mihara Y, Ushirozako H, Matsuyama Y (2019) The risk of proximal junctional kyphosis decreases in patients with optimal thoracic kyphosis. Spine Deform 7:759–770. https://doi.org/10.1016/j.jspd.2018.12.007
Le Huec JC, Thompson W, Mohsinaly Y, Barrey C, Faundez A (2019) Sagittal balance of the spine. Eur Spine J 28:1889–1905. https://doi.org/10.1007/s00586-019-06083-1
Acknowledgements
We express our appreciation to Sho Kobayashi and Daisuke Togawa for their assistance in collecting the cases and engaging in discussions regarding the manuscript. We would like to thank Editage (www.editage.jp) for English language editing.
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YM supervised the study. TH was responsible for the study’s conception and design. HU acquired, analysed, and interpreted the data; drafted the article; and approved the final version on behalf of all authors. All authors have critically revised the article and reviewed the submitted version.
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Dr. Yamato and Dr. Oe work for a donation-funded laboratory called the “Division of Geriatric Musculoskeletal Health”. Donations to this laboratory were received from Medtronic Sofamor Danek, Inc., Japan Medical Dynamic Marketing, Inc., and Meitoku Medical Institution Jyuzen Memorial Hospital. The other authors declare no conflicts of interest.
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The study protocol was approved by the Institutional Review Board of Hamamatsu University School of Medicine (No. 14-306). The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.
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Ushirozako, H., Hasegawa, T., Yamato, Y. et al. L5 pedicle subtraction osteotomy maintains good radiological and clinical outcomes in elderly patients with a rigid kyphosis deformity: a more than 2-year follow-up report. Eur Spine J 29, 3018–3027 (2020). https://doi.org/10.1007/s00586-020-06616-z
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DOI: https://doi.org/10.1007/s00586-020-06616-z