Skip to main content

Advertisement

Log in

Acute pancreatitis following scoliosis surgery: description and clinical course in 14 adolescents

  • Original Article
  • Published:
European Spine Journal Aims and scope Submit manuscript

Abstract

Purpose

Acute pancreatitis is a possible complication after scoliosis surgery. Although some risk factors have been documented in the literature, clinical description of pancreatitis diagnosis and ensuing course still remain very poor. The aim of this study was to describe characteristics of acute pancreatitis after scoliosis surgery.

Methods

A descriptive, retrospective and single-center study of fourteen adolescents with postoperative acute pancreatitis after spine fusion surgery in scoliosis management between April 2003 and August 2012 was performed.

Results

Acute pancreatitis occurred within 9.5 days (4–51) after surgery. Abdominal pain was atypical and was expressed in only half of the children. Ileus, nausea and vomiting were the most frequent signs. None of the acute pancreatitis cases was severe.

Conclusion

Acute pancreatitis is an early complication of scoliosis surgery. Clinical signs are atypical and non-severe and can induce misleading forms. Presence of delayed digestive problems should alert the clinician to the risk of pancreatitis in the aftermath of scoliosis surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

Abbreviations

AP:

Acute pancreatitis

BMI:

Body mass index

CT:

Computed tomography

CRP:

C-Reactive Protein

CVC:

Central venous catheter

GERD:

Gastroesophageal reflux disease

MOF:

Multiple organ failure

NVGR:

Nausea, vomiting or gastric residuals

RAD:

Reactive airway disease

References

  1. Haas GS, Warshaw AL, Daggett WM, Aretz HT (1985) Acute pancreatitis after cardiopulmonary bypass. Am J Surg 149(4):508–515

    Article  CAS  PubMed  Google Scholar 

  2. Levine SR, Gambill EE, Greene LF (1962) Acute pancreatitis following transurethral prostatic resection: report of six cases. J Urol 88:657–663

    CAS  PubMed  Google Scholar 

  3. Reeve TS, Delbridge LW (1982) Pancreatitis following parathyroid surgery. Ann Surg 195(2):158–162

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Borkhuu B, Nagaraju D, Miller F, Moamed Ali MH, Pressel D, Adelizzi-Delany J et al (2009) Prevalence and risk factors in postoperative pancreatitis after spine fusion in patients with cerebral palsy. J Pediatr Orthop 29(3):256–262

    Article  PubMed  Google Scholar 

  5. Laplaza FJ, Widmann RF, Fealy S, Moustafellos E, Illueca M, Burke SW et al (2002) Pancreatitis after surgery in adolescent idiopathic scoliosis: incidence and risk factors. J Pediatr Orthop 22(1):80–83

    PubMed  Google Scholar 

  6. He Z, Tonb DJF, Dabney KW, Miller F, Shah SA, Brenn BR et al (2004) Cytokine release, pancreatic injury, and risk of acute pancreatitis after spinal fusion surgery. Dig Dis Sci 49(1):143–149

    Article  PubMed  Google Scholar 

  7. Leichtner AM, Banta JV, Etienne N, Schwartz AN, Renshaw TS, Solari LD et al (1991) Pancreatitis following scoliosis surgery in children and young adults. J Pediatr Orthop 11(5):594–598

    Article  CAS  PubMed  Google Scholar 

  8. Bai HX, Lowe ME, Husain SZ (2011) What have we learned about acute pancreatitis in children? J Pediatr Gastroenterol Nutr 52(3):262–270

    Article  PubMed  PubMed Central  Google Scholar 

  9. Société Nationale Française de Gastro-Entérologie (2001) Consensus conference: acute pancreatitis. Gastroentérologie Clin Biol 25(2):177–192

    Google Scholar 

  10. AtlantaClassification[1].pdf. http://www.nghd.pt/nghd/images/stories/classification_of_pancreatitis.pdf

  11. Rajaraman V, Vingan R, Roth P, Heary RF, Conklin L, Jacobs GB (1999) Visceral and vascular complications resulting from anterior lumbar interbody fusion. J Neurosurg 91(1 Suppl):60–64

    CAS  PubMed  Google Scholar 

  12. Shapiro G, Green DW, Fatica NS, Boachie-Adjei O (2001) Medical complications in scoliosis surgery. Curr Opin Pediatr 13(1):36–41

    Article  CAS  PubMed  Google Scholar 

  13. Rapport_evaluation_de_lamylasemie_2009-07-27_16-57-49_72[1].pdf. http://www.has-sante.fr/portail/upload/docs/application/pdf/2009-07/rapport_evaluation_de_lamylasemie_2009-07-27_16-57-49_72.pdf

  14. Moreau J (2001) What is the gold standard for diagnosis? Gastroentérologie Clin Biol 25(1 Suppl):1S7–1S11

    CAS  Google Scholar 

  15. Vibert E, Becquemin JP, Rotman N, Mellière D (2002) Acute pancreatitis after surgical treatment of abdominal aortic aneurysm. Ann Chir 127(2):101–106

    Article  CAS  PubMed  Google Scholar 

  16. Ramsey PS, Podratz KC (1999) Acute pancreatitis after gynecologic and obstetric surgery. Am J Obstet Gynecol 181(3):542–546

    Article  CAS  PubMed  Google Scholar 

  17. Malka D, Rosa-Hézode I (2001) Positive and etiological diagnosis of acute pancreatitis. Gastroentérologie Clin Biol 25(1 Suppl):1S153–1S168

    CAS  Google Scholar 

  18. Yeung CY, Lee HC, Huang FY, Ho MY, Kao HA, Liang DC et al (1996) Pancreatitis in children–experience with 43 cases. Eur J Pediatr 155(6):458–463

    Article  CAS  PubMed  Google Scholar 

  19. Park AJ, Latif SU, Ahmad MU, Bultron G, Orabi AI, Bhandari V et al (2010) A comparison of presentation and management trends in acute pancreatitis between infants/toddlers and older children. J Pediatr Gastroenterol Nutr 51(2):167–170

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Korovessis PG, Stamatakis M, Baikousis A (1996) Relapsing pancreatitis after combined anterior and posterior instrumentation for neuropathic scoliosis. J Spinal Disord 9(4):347–350

    CAS  PubMed  Google Scholar 

  21. Farley FA, Caird MS (2001) Pancreatitis after posterior spinal fusion for adolescent idiopathic scoliosis. J Spinal Disord 14(3):268–270

    Article  CAS  PubMed  Google Scholar 

  22. Yadav D, Agarwal N, Pitchumoni CS (2002) A critical evaluation of laboratory tests in acute pancreatitis. Am J Gastroenterol 97(6):1309–1318

    Article  CAS  PubMed  Google Scholar 

  23. Bragg LE, Thompson JS, Burnett DA, Hodgson PE, Rikkers LF (1985) Increased incidence of pancreas-related complications in patients with post operative pancreatitis. Am J Surg 150(6):694–697

    Article  CAS  PubMed  Google Scholar 

  24. Uhl W, Büchler M, Malfertheiner P, Martini M, Beger HG (1991) PMN-elastase in comparisonwith CRP, antiproteases, and LDH as indicators of necrosis in human acute pancreatitis. Pancreas 6(3):253–259

    Article  CAS  PubMed  Google Scholar 

  25. Rau BM, Kemppainen EA, Gumbs AA, Büchler MW, Wegscheider K, Bassi C et al (2007) Early assessment of pancreatic infections and overall prognosis in severe acute pancreatitis by procalcitonin (PCT): a prospective international multicenterstudy. Ann Surg 245(5):745–754

    Article  PubMed  PubMed Central  Google Scholar 

  26. Tsirikos AI, Lipton G, Chang W-N, Dabney KW, Miller F (2008) Surgical correction of scoliosis in pediatric patients with cerebral palsy using the unit rod instrumentation. Spine 33(10):1133–1140

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Maalik El Bouyousfi.

Ethics declarations

Conflict of interest

No conflict of interest and no source of funding.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

El Bouyousfi, M., Leveque, C., Miladi, L. et al. Acute pancreatitis following scoliosis surgery: description and clinical course in 14 adolescents. Eur Spine J 25, 3316–3323 (2016). https://doi.org/10.1007/s00586-016-4595-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00586-016-4595-0

Keywords

Navigation