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The effect of human amniotic membrane as a covering layer on propylene mesh in decrease of adhesion after laparotomy in the rabbit

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Abstract

Each year, approximately 4 million abdominal surgeries are performed, and it is estimated that 10–20 % of these patients develop abdominal hernias at the incision point. Currently, the standard method for repair of such hernias is the use of polypropylene mesh, which has complications such as adhesions. Therefore, it is crucial and logical to search for a type of material which can reduce such complications. This study was conducted in order to determine surgical and histological outcomes of polypropylene mesh coated with human amniotic membrane (HAM) in comparison with polypropylene mesh on its own. Ten rabbits were divided into two equal groups, group I and II. A 5-cm incision was made along the abdomen of each rabbit. In group I, a 2 × 3 cm layer of polypropylene mesh was placed under the wall of the abdomen adjacent to the viscera. In group II, the procedure was identical except that the mesh was covered by a 4 × 6 cm layer of HAM too. After 3 weeks, all animals were sacrificed and tissue samples were provided from the abdominal wall and adjacent viscera to evaluate any adhesion and histological changes in each group. Microscopic evaluation was performed for all samples, and no significant statistical difference was found between groups. It seems that the use of HAM as a coating for polypropylene mesh could have a positive effect in reducing adhesions in the abdominal viscera.

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References

  • Abbasi HR, Tahmasebi S, Hosseini SV, Tanideh N, Monabati A, Mehrabani D (2005) Repair of esophageal full–thickness defects with expanded polytetraflouroethylene (PTFE) patch: an experimental study on dogs. J Appl Anim Res 28:89–92

    Google Scholar 

  • Abbasi HR, Yazdani S, Mehrabani D, Tanideh N, Vasei M, Rasekhi AR, Hosseini SV, Amini M (2008) Evaluation of mushroom catheter for diverting loop ileostomy: an experimental study in dog. J Appl Anim Res 33:25–28

    Article  Google Scholar 

  • An G, Walter RJ, Nagy K (2004) Closure of abdominal wall defects using acellular dermal matrix. J Trauma 56:1266–1275

    Article  PubMed  Google Scholar 

  • Bachman S, Ramshaw B (2008) Prosthetic material in ventral hernia repair: how do I choose? Surg Clin North Am 88:101–112

    Article  PubMed  Google Scholar 

  • Barlas M, Gokcora H, Erekul S, Dindar H, Yucesan S (1992) Human amniotic membrane as an intestinal patch for neomucosal growth in the rabbit model. J Pediatr Surg 27:597–601

    Article  CAS  PubMed  Google Scholar 

  • Bellón JM, Rodríguez M, García-Honduvilla N, Pascual G, Gómez Gil V, Buján J (2007) Peritoneal effects of prosthetic meshes used to repair abdominal wall defects: monitoring adhesions by sequential laparoscopy. J Laparoendosc Adv Surg Tech A 17:160–166

    Article  PubMed  Google Scholar 

  • Brunicardi FC, Andersen D, Billiar T, Dunn D, Hunter J, Matthews J, Pollock RE (2014) Schwartz’s principles of surgery, 10th edn. McGraw Hill Professional Publishing, New York, pp 1937–1940

    Google Scholar 

  • Campanelli G, Nicolosi FM, Pettinari D, Contessini Avesani E (2004) Prosthetic repair, intestinal resection, and potentially contaminated areas: Safe and feasible? Hernia 8:190–192

    Article  CAS  PubMed  Google Scholar 

  • Castro PM, Rabelato JT, Monteiro GG, del Guerra GC, Mazzurana M, Alvarez GA (2014) Laparoscopy versus laparotomy in the repair of ventral hernias: systematic review and meta-analysis. Arq Gastroenterol 51:205–211

    Article  PubMed  Google Scholar 

  • Di Loreto FP, Mangione A, Palmisano E, Cerda JI, Dominguez MJ, Ponce G, Bernaus M, Gaffuri S, Torresi G, Bianco S (2013) Dried human amniotic membrane as an antiadherent layer for intraperitoneal placing of polypropylene mesh in rats. Surg Endosc 27:1435–1440

    Article  PubMed  Google Scholar 

  • DuBay DA, Wang X, Adamson B, Kuzon WM Jr, Dennis RG, Franz MG (2006) Mesh incisional herniorrhaphy increases abdominal wall elastic properties: a mechanism for decreased hernia recurrences in comparison with suture repair. Surgery 140:14–24

    Article  PubMed  Google Scholar 

  • Ghahramani L, Jahromi AB, Dehghani MR, Ashraf MJ, Rahimikazerooni S, Rezaianzadeh A, Safarpour AR, Hosseini SV (2014) Evaluation of repair in duodenal perforation with human amniotic membrane: an animal model (dog). Int Adv Biomed Res 3:113

    Article  Google Scholar 

  • Kesting MR, Loeffelbein DJ, Steinstraesser L, Muecke T, Demtroeder C, Sommerer F, Hoelzle F, Wolff KD (2008a) Cryopreserved human amniotic membrane for soft tissue repair in rats. Ann Plast Surg 60:684–691

    Article  CAS  PubMed  Google Scholar 

  • Kesting MR, Wolff KD, Hohlweg-Majert B, Steinstraesser L (2008b) The role of allogenic amniotic membrane in burn treatment. J Burn Care Res 29:907–916

    Article  PubMed  Google Scholar 

  • Kolker AR, Brown DJ, Redstone JS, Scarpinato VM, Wallack MK (2005) Multilayer reconstruction of abdominal wall defects with acellular dermal allograft (AlloDerm) and component separation. Ann Plast Surg 55:36–41

    Article  CAS  PubMed  Google Scholar 

  • Kruse FE, Meller D (2001) Amniotic membrane transplantation for reconstruction of the ocular surface. Der Ophthalmologe Z Dtsch Ophthalmol Ges 98:801–810

    CAS  Google Scholar 

  • Kuriu Y, Yamagishi H, Otsuji E, Nakashima S, Miyagawa K, Yoshikawa T, Kin S, Nakase Y, Fukuda K, Okamoto K, Sakakura C, Hamuro J, Kurihara E, Hagiwara A (2009) Regeneration of peritoneum using amniotic membrane to prevent postoperative adhesions. Hepatogastroenterology 56:1064–1068

    PubMed  Google Scholar 

  • Liang H, Li C, Gao A, Liang P, Shao Y, Lin T, Zhang X (2012) Spinal duraplasty with two novel substitutes restored locomotor function after acute laceration spinal cord injury in rats. J Biomed Mater Res B Appl Biomater 100:2131–2140

    Article  PubMed  Google Scholar 

  • Luijendijk RW, Hop WC, van den Tol MP, de Lange DC, Braaksma MM, IJzermans JN, Boelhouwer RU, de Vries BC, Salu MK, Wereldsma JC, Bruijninckx CM, Jeekel J (2000) A comparison of suture repair with mesh repair for incisional hernia. N Engl J Med 343:392–398

    Article  CAS  PubMed  Google Scholar 

  • Mehrabani D, Sadeghi B, Ashraf MJ, Abbasi HR, Amini M, Tanideh N, Sabet B, Javan H, Vasei M, Hosseini SV (2009) Comparison of simple closure and polytetraflouroethylene (PTFE) patch methods for repair of rectovaginal fistula in dog. J Appl Anim Res 35:73–76

    Article  Google Scholar 

  • Mucke T, Loeffelbein DJ, Holzle F, Slotta-Huspenina J, Borgmann A, Kanatas AN, Mitchell DA, Wagenpfeil S, Wolff KD, Kesting MR (2010) Intraoral defect coverage with prelaminated epigastric fat flaps with human amniotic membrane in rats. J Biomed Mater Res B Appl Biomater 95:466–474

    Article  PubMed  Google Scholar 

  • Najibpour N, Jahantab MB, Hosseinzadeh M, Roshanravan R, Moslemi S, Rahimikazerooni S, Safarpour AR, Ghahramani L, Hosseini SV (2013) The effects of human amniotic membrane on healing of colonic anastomosis in dogs. Ann Color Res 1:97–100

    Article  Google Scholar 

  • Niknejad H, Peirovi H, Jorjani M, Ahmadiani A, Ghanavi J, Seifalian AM (2008) Properties of the amniotic membrane for potential use in tissue engineering. Eur Cell Mater 15:88–99

    CAS  PubMed  Google Scholar 

  • Petter-Puchner AH, Fortelny RH, Mika K, Hennerbichler S, Redl H, Gabriel C (2011) Human vital amniotic membrane reduces adhesions in experimental intraperitoneal onlay mesh repair. Surg Endosc 25:2125–2131

    Article  CAS  PubMed  Google Scholar 

  • Ramirez OM, Ruas E, Dellon AL (1990) "Components separation" method for closure of abdominal-wall defects: an anatomic and clinical study. Plast Reconstr Surg 86:519–526

    Article  CAS  PubMed  Google Scholar 

  • Ran L, Jin J, Xu Y, Bu Y, Song F (2014) Comparison of robotic surgery with laparoscopy and laparotomy for treatment of endometrial cancer: a meta-analysis. PLoS One 9, e108361

    Article  PubMed  PubMed Central  Google Scholar 

  • Roshanravan R, Ghahramani L, Hosseinzadeh M, Mohammadipour M, Moslemi S, Rezaianzadeh A et al (2014) A new method to repair recto-vaginal fistula: Use of human amniotic membrane in an animal model. Adv Biomed Res 3:114

    Article  PubMed  PubMed Central  Google Scholar 

  • Singh R, Chouhan US, Purohit S, Gupta P, Kumar P, Kumar A, Chacharkar MP, Kachhawa D, Ghiya BC (2004) Radiation processed amniotic membranes in the treatment of non-healing ulcers of different etiologies. Cell Tissue Bank 5:129–134

    Article  PubMed  Google Scholar 

  • Swan J (2014) Use of cryopreserved, particulate human amniotic membrane and umbilical cord (am/uc) tissue: a case series study for application in the healing of chronic wounds. Surg Technol Int 25:73–78

    PubMed  Google Scholar 

  • Uludag M, Citgez B, Ozkaya O, Yetkin G, Ozcan O, Polat N, Isgor A (2009a) Effects of amniotic membrane on the healing of primary colonic anastomoses in the cecal ligation and puncture model of secondary peritonitis in rats. Int J Color Dis 24:559–567

    Article  Google Scholar 

  • Uludag M, Citgez B, Ozkaya O, Yetkin G, Ozcan O, Polat N et al (2009b) Effects of amniotic membrane on the healing of normal and high-risk colonic anastomoses in rats. Int J Color Dis 24:809–817

    Article  Google Scholar 

  • Uludag M, Ozdilli K, Citgez B, Yetkin G, Ipcioglu OM, Ozcan O et al (2010) Covering the colon anastomoses with amniotic membrane prevents the negative effects of early intraperitoneal 5-FU administration on anastomotic healing. Int J Color Dis 25:223–232

    Article  Google Scholar 

  • Yetkin G, Uludag M, Citgez B, Karakoc S, Polat N, Kabukcuoglu F (2009) Prevention of peritoneal adhesions by intraperitoneal administration of vitamin E and human amniotic membrane. Int J Surg 7:561–565

    Article  PubMed  Google Scholar 

  • Zelen CM, Gould L, Serena TE, Carter MJ, Keller J, Li WW (2014) A prospective, randomised, controlled, multi-centre comparative effectiveness study of healing using dehydrated human amnion/chorion membrane allograft, bioengineered skin substitute or standard of care for treatment of chronic lower extremity diabetic ulcers. Int Wound J Nov 26. [Epub ahead of print]

  • Zinner JM, Ashley WS (2012) Maingot’s Abdominal Operations. 12th ed: McGraw-Hill Professional; p. 1328

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Acknowledgments

The authors wish to thank the financial support of Shiraz University of Medical Sciences.

Conflict of interest

The authors declare that they no competing interest.

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Authors and Affiliations

  1. Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Neda Najibpour, Alimohammad Bananzadeh, Abbas Rezaianzadeh & Seyed Vahid Hosseini

  2. Department of General Surgery, Al Hussein Teaching Hospital, Kerbala, Iraq

    Mohammed Ali Al Hurry Ahmed

  3. Department of General Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

    Mohammad Rezazadeh Kermani

  4. Department of Surgery, Al-Karama Teaching Hospital Medical College, Wasit University, Wasit, Iraq

    Khairallah Muzhir Gabash

  5. School of Medicine, Ahvaz Jundishapur, University of Medical Sciences, Ahvaz, Iran

    Hossein Tajali

  6. Stem Cell and Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Davood Mehrabani

Authors
  1. Neda Najibpour
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  2. Mohammed Ali Al Hurry Ahmed
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  3. Alimohammad Bananzadeh
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  4. Abbas Rezaianzadeh
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  5. Mohammad Rezazadeh Kermani
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  6. Khairallah Muzhir Gabash
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  7. Hossein Tajali
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  8. Seyed Vahid Hosseini
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  9. Davood Mehrabani
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Correspondence to Seyed Vahid Hosseini.

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Najibpour, N., Ahmed, M.A.A.H., Bananzadeh, A. et al. The effect of human amniotic membrane as a covering layer on propylene mesh in decrease of adhesion after laparotomy in the rabbit. Comp Clin Pathol 25, 131–135 (2016). https://doi.org/10.1007/s00580-015-2153-5

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  • DOI: https://doi.org/10.1007/s00580-015-2153-5

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