Abstract
Background and aims
The quality of colonoscopy is essential for successful colon cancer screening. Inadequate polypectomy technique can contribute to incomplete polypectomy. The primary outcome of this study was to compare the incomplete resection rate (IRR) for cold jumbo forceps polypectomy (JFP) and cold snare polypectomy (CSP). Secondary outcomes were to compare the rates of tissue retrieval and rates of procedure-related complications.
Methods
This prospective randomized parallel-group study assigned patients undergoing colonoscopy to jumbo biopsy forceps polypectomy (JFP) or cold snare polypectomy (CSP) for polyps ≤ 6 mm in size. After polyp removal was complete, the base of the polypectomy site was biopsied to evaluate for the presence of residual polyp tissue.
Results
The resection quality was evaluated in 151 patients with 261 polyps ≤ 6 mm. The IRR was 9.6% (25/261) for all polyps, 11.1% (16/144) for JFP, and 7.7% (9/117) for CSP (P = 0.41). Failure of tissue retrieval was noted in 0/144 (0%) of JFP and 5/117 (4.3%) of CSP (P = 0.02). There were no procedure-related complications in either group.
Conclusion
Colon polyps are incompletely resected in a small but potentially significant percentage of cases. IRR are similar with the use of cold jumbo forceps and cold snare. Use of cold jumbo forceps may result in more successful tissue retrieval as compared to cold snare.
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Abbreviations
- UCSD:
-
University of California San Diego
- VA:
-
Veterans Affairs
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Acknowledgements
The authors wish to thank Shahrokh Golshan for assistance with the statistical analysis, and Amelia Parnell for the preparation of this manuscript for submission.
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An unrestricted educational grant funding from SpectraScience was used for this study. There were no institutional or corporate affiliations associated with this study.
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Shireena Desai, Samir Gupta, Nedret Copur-Dahi, and Mary L. Krinsky have no conflicts of interest or financial ties to disclose.
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Desai, S., Gupta, S., Copur-Dahi, N. et al. A prospective randomized study comparing jumbo biopsy forceps to cold snare for the resection of diminutive colorectal polyps. Surg Endosc 34, 1206–1213 (2020). https://doi.org/10.1007/s00464-019-06874-z
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DOI: https://doi.org/10.1007/s00464-019-06874-z