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Modified laparoscopic and open splenectomy and azygoportal disconnection for portal hypertension

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Abstract

Background

Laparoscopic splenectomy and azygoportal disconnection has been reported safe, feasible and minimally invasive for patients with portal hypertension. We have developed an even less invasive technique, modified laparoscopic splenectomy and azygoportal disconnection, and compared outcomes of modified laparoscopic splenectomy and azygoportal disconnection and open splenectomy and azygoportal disconnection in patients with portal hypertension.

Methods

We retrospectively evaluated outcomes in 107 cirrhotic patients with portal hypertensive bleeding and secondary hypersplenism who underwent modified laparoscopic splenectomy and azygoportal disconnection (n = 37) or open splenectomy and azygoportal disconnection (n = 70) between January 2010 and February 2013. Their demographic, intraoperative, and postoperative variables were compared.

Results

Modified laparoscopic splenectomy and azygoportal disconnection was successful in all patients, with none requiring conversion to open surgery or having significant perioperative complications. Operation time was significantly longer for modified laparoscopic splenectomy and azygoportal disconnection than open splenectomy and azygoportal disconnection (P < 0.0001), but estimated intraoperative blood loss (P = 0.0004); volume of intraoperative blood transfusion (P < 0.05); visual analog scale pain score on the first postoperative day (P < 0.0001); times to first oral intake (P < 0.0001), passage of flatus (P = 0.0004), and off-bed activity (P < 0.0001); postoperative hospital stay (P < 0.0001); postoperative days of temperature >38.0 °C (P = 0.002); white blood cell counts on postoperative days 1 (P < 0.0001) and 7 (P < 0.05) were significantly reduced in the modified laparoscopic splenectomy and azygoportal disconnection group. The percentage of patients experiencing postoperative complications was significantly lower in the modified laparoscopic splenectomy and azygoportal disconnection group than in the open splenectomy and azygoportal disconnection group (13.5 % [5/37] vs. 35.7 % [25/70], P < 0.05).

Conclusions

The less invasive modified laparoscopic splenectomy and azygoportal disconnection group is a feasible, effective, and safe surgical procedure for liver cirrhosis patients with portal hypertensive bleeding and hypersplenism.

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Disclosures

Drs. D.-S. Bai, J.-J. Qian, P. Chen, J. Yao, X.-D. Wang, S.-J. Jin, and G.-Q. Jiang have no conflict of interest or financial ties to disclose.

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Authors and Affiliations

  1. Department of Hepatobiliary Surgery, Clinical Medical College of Yangzhou University, 98 West Nantong Rd, Yangzhou, 225000, China

    Dou-Sheng Bai, Jian-Jun Qian, Ping Chen, Jie Yao, Xiao-Dong Wang, Sheng-Jie Jin & Guo-Qing Jiang

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  1. Dou-Sheng Bai
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  2. Jian-Jun Qian
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  3. Ping Chen
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  4. Jie Yao
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  5. Xiao-Dong Wang
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  7. Guo-Qing Jiang
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Corresponding author

Correspondence to Guo-Qing Jiang.

Additional information

Drs. Dou-Sheng Bai, Jian-Jun Qian, and Ping Chen contributed equally to this work.

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Bai, DS., Qian, JJ., Chen, P. et al. Modified laparoscopic and open splenectomy and azygoportal disconnection for portal hypertension. Surg Endosc 28, 257–264 (2014). https://doi.org/10.1007/s00464-013-3182-2

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  • DOI: https://doi.org/10.1007/s00464-013-3182-2

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