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Retinal detachment and uveitis at a tertiary center over 10 years: the King Khaled Eye Specialist Hospital (KKESH) Uveitis Survey Study Group

  • Retinal Disorders
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Abstract

Purpose

To evaluate the frequency, etiology, treatment, and visual prognosis of retinal detachment (RD) in patients with uveitis.

Methods

A retrospective review was performed in 707 consecutive patients (1042 eyes) with uveitis, of whom 97 (13.7%) (157 eyes [15.1%]) had RD.

Results

There were 126 (12.1%) eyes with exudative retinal detachment (ERD), 16 (1.5%) with tractional retinal detachment (TRD), and 15 (1.4%) with rhegmatogenous retinal detachment (RRD). Panuveitis was most commonly associated with RD (144 (91.1%) eyes). Infectious causes were more common in RRD, and non-infectious etiologies were most common in ERD and TRD. Oral prednisone was the initial therapy in ERD. Additionally, in these cases, cyclosporine was prescribed most frequently (47.1% patients), followed by azathioprine (26.4% patients). Fourteen (87.5%) eyes with TRD and all RRD cases underwent surgery. In patients with ERD, the mean best-corrected visual acuity (BCVA) was 1.1 ± 0.7 LogMAR at baseline and 0.6 ± 0.2 LogMAR at last visit (p = 0.001). In patients with TRD, mean BCVA was 0.7 ± 0.4 LogMAR at baseline and 0.6 ± 0.4 LogMAR at last visit (p = 0.056). In patients with RRD, mean BCVA was 1.6 ± 0.9 LogMAR at baseline and 20 1.3 ± 0.9 LogMAR at last visit (p = 0.185).

Conclusion

In Saudi Arabia, ERD is observed in 12.1% of the eyes with uveitis, and less than 2% of eyes had TRD or RRD. Visual prognosis is usually good after ERD. Infection is the most frequent cause of RRD associated with uveitis and the visual prognosis is poor.

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References

  1. Tomkins-Netzer O, Talat L, Bar A et al (2014) Long-term clinical outcome and causes of vision loss in patients with uveitis. Ophthalmology 121:2387–2392

    Article  PubMed  Google Scholar 

  2. Kerkhoff FT, Lamberts QJ, van den Biesen PR et al (2003) Rhegmatogenous retinal detachment and uveitis. Ophthalmology 110:427–431

    Article  PubMed  Google Scholar 

  3. Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group (2005) Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 140:509–516

    Article  Google Scholar 

  4. Nussenblatt RB, Palestine AG, Chan CC, Roberge F (1985) Standardization of vitreal inflammatory activity in intermediate and posterior uveitis. Ophthalmology 92:467–471

    Article  CAS  PubMed  Google Scholar 

  5. Jumper JM, Machemer R, Gallemore RP, Jaffe GJ (2000) Exudative retinal detachment and retinitis associated with acquired syphilitic uveitis. Retina 20:190–194

    Article  CAS  PubMed  Google Scholar 

  6. Bowyer JD, Gormley PD, Seth R et al (1999) Choroidal tuberculosis diagnosed by polymerase chain reaction. A clinicopathologic case report. Ophthalmology 106:290–294

    Article  CAS  PubMed  Google Scholar 

  7. Bialasiewicz AA, Ruprecht KW, Naumann GOH, Blenk H (1988) Bilateral diffuse choroiditis and exudative retinal detachments with evidence of Lyme disease. Am J Ophthalmol 105:419–420

    Article  CAS  PubMed  Google Scholar 

  8. Kerkhoff FT, Rothova A (2000) Bartonella henselae associated uveitis and HLA-B27. Br J Ophthalmol:1125–1129

  9. Thompson MJ, Albert DM (2005) Ocular tuberculosis. Arch Ophthalmol 123(6):844–849

    Article  PubMed  Google Scholar 

  10. Pollack AL, McDonald HR, Johnson RN et al (2002) Peripheral retinoschisis and exudative retinal detachment in pars planitis. Retina 22:719–722

    Article  PubMed  Google Scholar 

  11. Brockhurst RJ. (1981) Retinoschisis: complication of peripheral uveitis. Arch Ophthalmol 99: 1998–1999

  12. Jalil A, Dhawahir-Scala FE, Jones NP (2010) Nonprogressive tractional inferior retinal elevation in intermediate uveitis. Ocul Immunol Inflamm 18:60–63

    Article  CAS  PubMed  Google Scholar 

  13. De Hoog J, Ten Berge JC, Groen F, Rothova A (2017) Rhegmatogenous retinal detachment in uveitis. J Ophthalmic Inflamm Infect 7(1):22

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Hagler WS, Jarrett WH II, Chang M (1978) Rhegmatogenous retinal detachment following chorioretinal inflammatory disease. Am J Ophthalmol 86:373–379

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Maumenee 708, Baltimore, MD, 21287, USA

    J. Fernando Arevalo

  2. Retina and Vitreous Service, Clinica Privada de Ojos, Mar del Plata, Buenos Aires, Argentina

    Andres F. Lasave

  3. Uveitis Division, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia

    Turki Abdullah Al Ghamdi, Vishali Gupta, Igor Kozak & Hassan A. Al Dhibi

Authors
  1. J. Fernando Arevalo
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  2. Andres F. Lasave
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  3. Turki Abdullah Al Ghamdi
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  4. Vishali Gupta
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  5. Igor Kozak
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  6. Hassan A. Al Dhibi
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Consortia

The KKESH Uveitis Survey Study Group

Corresponding author

Correspondence to J. Fernando Arevalo.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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For a complete listing of the participating members of The KKESH Uveitis Survey Study Group, see Appendix.

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Arevalo, J.F., Lasave, A.F., Al Ghamdi, T.A. et al. Retinal detachment and uveitis at a tertiary center over 10 years: the King Khaled Eye Specialist Hospital (KKESH) Uveitis Survey Study Group. Graefes Arch Clin Exp Ophthalmol 257, 1857–1861 (2019). https://doi.org/10.1007/s00417-019-04378-z

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  • DOI: https://doi.org/10.1007/s00417-019-04378-z

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