References
Simpson D, Noble S, Perry C (2002) Glatiramer acetate: a review of its use in multiple sclerosis. CNS Drugs 16:825–850
Frese A, Bethke F, Lüdemann P, Stögbauer F (2000) Development of myasthenia gravis in a patient with multiple sclerosis during treatment with glatiramer acetate. J Neurol 247:713
Heesen C, Gbadamosi J, Schoser BG, Pohlau D (2001) Autoimmune hyperthyroidism in multiple sclerosis under treatment with glatiramer acetate-a case report. Eur J Neurol 8:199
Seyfert S, Klapps P, Meisel C, Fischer T, Junghan U (1990) Multiple sclerosis and other immunologic diseases. Acta Neurol Scand 81:37–42
de Seze J, Canva-Delcambre V, Fajardy I, Delalande S, Stojkovic T, Godet E, Vermersch P (2005) Autoimmune hepatitis and multiple sclerosis: a coincidental association? Mult Scler 11:691–693
Aharoni R, Teitelbaum D, Sela M, Arnon R (1997) Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 94:10821–10826
Miller A, Shapiro S, Gershtein R, Kinarty A, Rawashdeh H, Honigman S, Lahat N (1998) Treatment of multiple sclerosis with copolymer-1 (Copaxone): implicating mechanisms of Th1 to Th2/Th3 immune-deviation. J Neuroimmunol 92:113–121
Venkatesh YP, Hegde VL (2003) A hypothesis for the mechanism of immediate hypersensitivity to mannitol. Allergol Int 52:165–170
Speciale L, Saresella M, Caputo D, Ruzzante S, Mancuso R, Calvo MG, Guerini FR, Ferrante P (2000) Serum auto antibodies presence in multiple sclerosis patients treated with beta-interferon 1a and 1b. J Neurovirol 2:57–61
Pulicken M, Koteish A, DeBusk K, Calabresi PA (2006) Unmasking of autoimmune hepatitis in a patient with MS following interferon beta therapy. Neurology 66:1954–1955
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Neumann, H., Csepregi, A., Sailer, M. et al. Glatiramer acetate induced acute exacerbation of autoimmune hepatitis in a patient with multiple sclerosis. J Neurol 254, 816–817 (2007). https://doi.org/10.1007/s00415-006-0441-3
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DOI: https://doi.org/10.1007/s00415-006-0441-3