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High stimulus rate brainstem auditory evoked potential in benign paroxysmal positional vertigo

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Abstract

The objective of this study is to use high (49/s) and low (9/s) stimulation rates of the BAEP to investigate the possible mechanism responsible for BPPV. A total of 81 patients (55 women and 26 men, mean age ± SD = 54.6 ± 15.0) with idiopathic BPPV, as well as 106 control subjects (70 women and 36 men, mean age ± SD = 51.2 ± 16.3) participated in the study. The results of high (49/s) and low (9/s) stimulation rates of the BAEP test were compared and analyzed. The difference in BAEP wave I peak latencies between low and high stimulation rate (DPL I) and BAEP wave I peak latency in high stimulation (HPL I) of affected ears (0.24 ± 0.14 and 1.91 ± 0.21 ms) in BPPV patients were significantly prolonged when compared with the controls (0.10 ± 0.08 and 1.76 ± 0.18 ms) and unaffected ears (0.12 ± 0.10 and 1.82 ± 0.21 ms) (p < 0.001). The abnormal rate of DPL I in the affected ear (52/83, 62.65 %) was significantly higher than that in the unaffected ear (7/79, 8.86 %) and the normal left ear (4/106, 3.77 %). We suggest that ischemia of the inner ear might be one of the causes of BPPV and that DPL I may be used to assess the ischemic degree in subjects over 20 years old.

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Acknowledgments

This work was supported by funding from the Chongqing Municipal Education Commission (no. KJ080307) and the Chongqing Bureau of Health (no. 2013-1-012).

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Neurology, The First Affiliated Hospital, Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China

    Juan-Wen He, Qiang Gong, Xue-Feng Wang & Zheng Xiao

  2. Department of Neurology, Deyang People’s Hospital, Deyang, China

    Qiang Gong

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  1. Juan-Wen He
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  2. Qiang Gong
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  3. Xue-Feng Wang
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  4. Zheng Xiao
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Correspondence to Zheng Xiao.

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He, JW., Gong, Q., Wang, XF. et al. High stimulus rate brainstem auditory evoked potential in benign paroxysmal positional vertigo. Eur Arch Otorhinolaryngol 272, 2095–2100 (2015). https://doi.org/10.1007/s00405-014-3172-6

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  • DOI: https://doi.org/10.1007/s00405-014-3172-6

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