Abstract
Cervicofacial necrotising fasciitis (CNF) is a potentially fatal infection which can occasionally present in the head and neck. An early diagnosis and aggressive treatment is imperative for minimising the associated mortality and morbidity. The early clinical features are usually non-specific which makes it difficult to differentiate it from other less serious infections. Necrosis of the skin is a late feature. Although it is more common in the immunocompromised, it can also affect normal individuals. We discuss our experience of five patients with CNF, review of literature and algorithm for early diagnosis of CNF. With experience, we were able to diagnose the subsequent cases early and minimise the mortality and morbidity. In conclusion, the incidence of CNF has increased in the last decade partly due to an increased clinical awareness. Early intervention is essential to minimise the mortality and morbidity. It should be managed by a team of at least otolaryngologists, intensivist, microbiologist and plastic surgeons; cardiothoracic surgeons may be required. Treatment involves early aggressive surgical debridement/fasciotomy, intravenous antibiotics and general metabolic support in the intensive care unit.
Similar content being viewed by others
References
Hohlweg-Majert Bettina, Weyer Nils, Metzger MarcC, Schon Ralf (2006) Cervicofacial necrotizing fasciitis. Diabetes Res Clin Pract 72:206–208
Panda NK, Simhadri S, Sridhara SR (2004) Cervicofacial necrotizing fasciitis: can we expect a favourable outcome? J Laryngol Otol 118:771–777
Rouse TM, Melangoni MA, Schulte WJ (1982) Necrotizing fascitis: a preventable disaster. Surgery 92:765–770
Hassell M, Fagan P, Carson P, Currie BJ (2004) Streptococcal necrotising fasciitis from diverse strains of Streptococcus pyogenes in tropical Northern Australia: case series and comparison with the literature. BMJ Infect Dis 4:60. doi:10.1186/1471-2334-4-60
Dallan I, Mandoli A, Lucchesi C, Bruschini L, Seginini G, Casani AP (2004) Cranio-cervical necrotizing fasciitis: case report and review of the literature. Acta Otorhinolaryngol Ital 24:83–86
Elliott DC, Kufera JA, Myers RAM (1996) Necrotizing soft tissue infections: risk factors for mortality and strategies for management. Ann Surg 224:672–683
Mohammedi I, Ceruse P, Duperret S, Vedrinne JM, Bouletreau P (1999) Cervical necrotizing fasciitis: 10 years’ experience at a single institution. Intensive Care Med 25:829–834
Rapoport Y, Himelfarb MZ, Zikk D, Bloom J (1991) Cervical necrotizing fasciitis of odontogenic origin. Oral Surg Oral Med Oral Pathol 72:15–18
Taviloglu K, Cabioglu N, Cagatay A, Yahar H et al (2005) Idiopathic necrotizing fasciitis: risk factors and strategies for management. Am Surg 71(4):315–320
Kantu S, Har-El G (1997) Cervical necrotizing fasciitis. Ann Otol Rhinol Laryngol 106(11):965–970
Stone HH, Martin JD Jr (1972) Synergistic necrotizing cellulitis. Ann Surg 175:702–710
Giuliano A, Lewis F Jr, Hadley K et al (1977) Bacteriology of necrotizing fasciitis. Am J Surg 134:53–56
Moss RM, Kunpittaya S, Sorasuchart A (1990) Cervical necrotizing fasciitis: an uncommon sequelae to dental infection. Ann Otol Rhinol Laryngol 99:643–646
Jain D, Kumar Y, Vasishta RK, Rajesh L, Pattari SK, Chakrabarti A (2006) Zygomycotic necrotizing fasciitis in immunocompetent patients: a series of 18 patients. Mod Pathol 19:1221–1226
Bilton BD, Zibari GB, McMillan RW, Aultman DF, Dunn G, McDonald J (1998) Aggressive surgical management of necrotizing fasciitis serves to decrease mortality: a retrospective study. Am Surg 64(5):397–401
McMahon J, Lowe T, Koppel DA (2003) Necrotizing soft tissue infections of the head and neck: case reports and literature review. Oral Surg Oral Med Oral Pathol 95(1):30–37
Johnson DE (2003) When pain is out of proportion. Emerg Med Serv 32(9):115–119
Kaplan DM, Fliss DM, Shulman H, Leiberman A (1995) Computed tomographic detection of necrotizing soft tissue infection of dental origin. Ann Otol Rhinol Laryngol 104:164–166
Arslan A, Pierre-Jerome C, Borthne A (2000) Necrotizing fasciitis: unreliable MRI findings in preoperative diagnosis. Eur J Radiol 36(3):139–143
Scmid MR, Kossmann T, Duewell S (1998) Differentiation of necrotizing fasciitis and cellulites using MR imaging. Am J Roentgenol 170:615–620
Chang-Chien CH (2006) Bacteraemic necrotizing fasciitis with compartment syndrome caused by non-O1 Vibrio cholerae. J Plast Reconstr Aesthet Surg 59(12):1381–1384 Epub 2006 Sep 6
Lee CH, Liu JW (2004) Right arm pyomyositis and necrotizing fasciitis complicated with subcutaneous emphysema and pneumomediastinum in a patient with diabetes mellitus and iatrogenic Cushing syndrome. South Med J 97(11):1104–1106
Dellinger EP (1991) Necrotizing soft-tissue infections. In: Davis JM, Shires GT (eds) Principles and management of surgical infections. Lippincott, Philadelphia, pp 23–29
Barillo DJ, McManus AT, Cancio LC, Sofer A, Goodwin CW (2003) Burn centre management of necrotizing fasciitis. J Burn Care Rehabil 24(3):127–132
Edlich RF, Winters KL, Woodard CR, Britt LD, Long WB (2005) Massive soft tissue infections: necrotizing fasciitis and purpura fulminans. J Long Term Eff Med Implants 15(1):57–65
Brown DR, Davis NL, Lepawsky M, Cunningham J, Kortbeek J (1994) A multi-centre review of the treatment of major truncal necrotizing infections with and without hyperbaric oxygen therapy. Am J Surg 167:485–489
Gozal D, Ziser A, Shupak A, Ariel A, Melamed Y (1986) Necrotizing fasciitis. Arch Surg 121:233–235
Shupak A, Shoshani O, Goldenberg I, Barzilai A, Moskuna R, Bursztein S (1995) Necrotizing fasciitis: an indication for hyperbaric oxygenation therapy? Surgery 118:873–878
Preuss SF, Stenzel MJ, Esriti A (2004) The successful use of maggots in necrotizing fasciitis of the neck: a case report. Head Neck 26:747–750
Acknowledgments
The authors gratefully acknowledge Mrs. Sue Warburton for her kind assistance with medical records.
Conflict of interest statement
None.
Author information
Authors and Affiliations
Corresponding author
Appendix: algorithm for management of CNF
Appendix: algorithm for management of CNF
Rights and permissions
About this article
Cite this article
Malik, V., Gadepalli, C., Agrawal, S. et al. An algorithm for early diagnosis of cervicofacial necrotising fasciitis. Eur Arch Otorhinolaryngol 267, 1169–1177 (2010). https://doi.org/10.1007/s00405-010-1248-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00405-010-1248-5