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The morbidity of sexual dysfunction of 125 Chinese women following different types of radical hysterectomy for gynaecological malignancies

  • Gynecologic Oncology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

Due to early detection and effective treatment, quality of sexual life of patients with gynaecological malignancies has become an important issue. However, the morbidity of sexual dysfunction and the proportion of different kinds of sexual dysfunction after radical hysterectomy are unclear. The aim of the current study was to assess the morbidity of sexual dysfunction and to conduct multivariate logistic regression analysis of patients’ sexual dysfunction.

Methods

Between July 2007 and December 2012, 125 women underwent radical hysterectomy, modified radical hysterectomy, and nerve-sparing radical hysterectomy were administered a self-reported sexual function questionnaire.

Results

The preoperative, and 1- and 2-year postoperative sexual dysfunction rates were 50.5% (50/99), 86.9% (93/107), and 92.3% (72/78), respectively. The incidence rates of sexual desire disorders before operation, at postoperative year 1, and at postoperative year 2 were 14.7% (14/95), 42.1% (45/107), and 51.9% (40/77), respectively. The preoperative incidence rates of sexual arousal disorders, orgasmic disorders, and sexual pain disorders were 18.4% (18/98), 51.1% (48/94), and 10.9% (11/101), respectively. At postoperative years 1 and 2, these were 38.8% (31/80), 81.0% (64/79), and 24.4% (20/82), and 49.1% (26/53), 84.6% (44/52), and 30.2% (16/53), respectively. Multivariable regression analysis revealed that age, preserved ovary, preserved posterior vaginal wall length, preoperative stage, radiotherapy, and education background were risk factors associated with sexual dysfunction.

Conclusion

The patients following radical hysterectomy had a high incidence of sexual dysfunction, which plateaued in postoperative years 1 and 2.

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Acknowledgements

The authors would like to thank professor of statistics Shengli An for his help with data acquisition and statistical analysis. This research was supported by a grant from Nanfang Hospital of Southern Medical University: Guangdong Province Science and Technology Plan Project (2012B031800392); The Twelfth Five-year National Science and Technology Support Project of Ministry of Science and Technology (2014BAI05B03); Guangzhou Science and Technology Plan (201508020264); and the Natural Science Foundation of Guangdong Province (2015A030311024).

Funding

This study was funded by Nanfang Hospital of Southern Medical University: Guangdong Province Science and Technology Plan Project (2012B031800392); The Twelfth Five-year National Science and Technology Support Project of Ministry of Science and Technology (2014BAI05B03); Guangzhou Science and Technology Plan (201508020264); and the Natural Science Foundation of Guangdong Province (2015A030311024).

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Nanfang Hospital of Southern Medical University, No. 1838, Guangzhou Avenue, Guangzhou, 510515, People’s Republic of China

    Xueqin Wang, Chunlin Chen, Ping Liu, Weili Li, Liling Wang & Yunlu Liu

  2. Department of Obstetrics and Gynecology, The Fifth Affiliated Hospital of Southern Medical University, No. 566, CongCheng Road, Conghua District, Guangzhou, 510900, People’s Republic of China

    Xueqin Wang

Authors
  1. Xueqin Wang
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  2. Chunlin Chen
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  3. Ping Liu
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  4. Weili Li
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  5. Liling Wang
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  6. Yunlu Liu
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Contributions

CC: project development and manuscript editing. XW: data collection, data analysis, and manuscript writing. PL: project development and data collection. WL: data management and data analysis. YL: data collection. LW: data collection.

Corresponding author

Correspondence to Chunlin Chen.

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Conflict of interest

Xueqin Wang declares that she has no conflict of interest. Chunlin Chen declares that he has no conflict of interest. Ping Liu declares that she has no conflict of interest. Weili Li declares that he has no conflict of interest. Liling Wang declares that he has no conflict of interest. Yunlu Liu declares that she has no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Wang, X., Chen, C., Liu, P. et al. The morbidity of sexual dysfunction of 125 Chinese women following different types of radical hysterectomy for gynaecological malignancies. Arch Gynecol Obstet 297, 459–466 (2018). https://doi.org/10.1007/s00404-017-4625-0

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  • DOI: https://doi.org/10.1007/s00404-017-4625-0

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