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Reply to: Pelargonidin and its glycosides as dietary chemopreventives attenuating inflammatory bowel disease symptoms through the aryl hydrocarbon receptor

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References

  1. Ghattamaneni NK, Sharma A, Panchal SK, Brown L (2019) Pelargonidin 3-glucoside-enriched strawberry attenuates symptoms of DSS-induced inflammatory bowel disease and diet-induced metabolic syndrome in rats. Eur J Nutr. https://doi.org/10.1007/s00394-019-02130-1

    Article  PubMed  Google Scholar 

  2. Bhaswant M, Fanning K, Netzel M, Mathai ML, Panchal SK, Brown L (2015) Cyanidin 3-glucoside improves diet-induced metabolic syndrome in rats. Pharmacol Res 102:208–217. https://doi.org/10.1016/j.phrs.2015.10.006

    Article  CAS  PubMed  Google Scholar 

  3. Ghattamaneni NKR, Panchal SK, Brown L (2019) Cyanidin 3-glucoside from Queen Garnet plums and purple carrots attenuates DSS-induced inflammatory bowel disease in rats. J Funct Foods 56:194–203. https://doi.org/10.1016/j.jff.2019.01.028

    Article  CAS  Google Scholar 

  4. Biagioli M, Carino A, Fiorucci C, Annunziato G, Marchianò S, Bordoni M, Roselli R et al (2019) The aryl hydrocarbon receptor (AhR) mediates the counter-regulatory effects of pelargonidins in models of inflammation and metabolic dysfunctions. Nutrients 11(8):1820. https://doi.org/10.3390/nu11081820

    Article  CAS  PubMed Central  Google Scholar 

  5. Jaeger C, Tischkau SA (2016) Role of aryl hydrocarbon receptor in circadian clock disruption and metabolic dysfunction. Environ Health Insights 10:133–141. https://doi.org/10.4137/ehi.S38343

    Article  PubMed  PubMed Central  Google Scholar 

  6. Natividad JM, Agus A, Planchais J, Lamas B, Jarry AC, Martin R, Michel ML et al (2018) Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome. Cell Metab 28(5):737–749. https://doi.org/10.1016/j.cmet.2018.07.001

    Article  CAS  PubMed  Google Scholar 

  7. Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Anzenbacher P, Dvorak Z (2013) Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicol Lett 218(3):253–259. https://doi.org/10.1016/j.toxlet.2013.01.020

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Zapletalova M, Anzenbacher P et al (2013) Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicol Lett 221(1):1–8. https://doi.org/10.1016/j.toxlet.2013.05.007

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Jayarathne S, Stull AJ, Park OH, Kim JH, Thompson L, Moustaid-Moussa N (2019) Protective effects of anthocyanins in obesity-associated inflammation and changes in gut microbiome. Mol Nutr Food Res 63(20):e1900149. https://doi.org/10.1002/mnfr.201900149

    Article  CAS  PubMed  Google Scholar 

  10. Farzaei MH, El-Senduny FF, Momtaz S, Parvizi F, Iranpanah A, Tewari D, Naseri R et al (2018) An update on dietary consideration in inflammatory bowel disease: anthocyanins and more. Expert Rev Gastroenterol Hepatol 12(10):1007–1024. https://doi.org/10.1080/17474124.2018.1513322

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Lindsay Brown.

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This reply refers to a Letter to the Editor available here: https://doi.org/10.1007/s00394-020-02316-y

This Reply refers to the original publication available under https://doi.org/10.1007/s00394-019-02130-1.

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Ghattamaneni, N.K.R., Sharma, A., Panchal, S.K. et al. Reply to: Pelargonidin and its glycosides as dietary chemopreventives attenuating inflammatory bowel disease symptoms through the aryl hydrocarbon receptor. Eur J Nutr 59, 3865–3866 (2020). https://doi.org/10.1007/s00394-020-02315-z

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  • DOI: https://doi.org/10.1007/s00394-020-02315-z

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