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Long-term functional outcome of sacrococcygeal teratoma after resection in neonates and infants: a single-center experience

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Abstract

Purpose

This study aimed to evaluate the incidence and factors associated with long-term functional outcomes of sacrococcygeal teratoma (SCT) after resection in neonates and infants.

Methods

Twenty-nine patients with a minimum of 3 years of follow-up who underwent resection and were histologically diagnosed with SCTs between 1982 and 2017 at our institution were included.

Results

The median age at the time of the study was 10.0 years. Functional disorders occurred after surgery in 6 (20.7%) patients. Anorectal dysfunction, urologic dysfunction, and lower-extremity motor disorders occurred in 6 (20.7%), 4 (13.8%), and 3 (10.3%) patients, respectively. One patient with all three types of functional disorders developed intestinal perforation due to ileus and died of sepsis at 13 years of age. The overall mortality rate after tumor resection was 3.4%. The patients who developed functional disorders presented a low 1-min Apgar score, larger tumors requiring abdominosacral resection, surgical injury to the pelvic organs, and immature or malignant histological findings.

Conclusion

Although the mortality rate was low, the long-term rate of functional disorders after SCT resection was approximately 20%. SCT patients with large tumors, surgical injury to the pelvic organs, and immature or malignant histological findings require thorough follow-up.

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Authors and Affiliations

  1. Department of Pediatric Surgery, Osaka Women’s and Children’s Hospital, Izumi, Japan

    Kazunori Masahata, Katsutoshi Makino, Takatoshi Abe, Kiyokazu Kim, Taku Yamamichi, Ai Tayama, Hideki Soh & Noriaki Usui

  2. Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Japan

    Kazunori Masahata

  3. Department of Clinical Pathology, Osaka Women’s and Children’s Hospital, Izumi, Japan

    Chihiro Ichikawa

Authors
  1. Kazunori Masahata
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  2. Chihiro Ichikawa
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  3. Katsutoshi Makino
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  4. Takatoshi Abe
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  5. Kiyokazu Kim
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  6. Taku Yamamichi
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  7. Ai Tayama
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  8. Hideki Soh
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  9. Noriaki Usui
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Correspondence to Kazunori Masahata.

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All authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Masahata, K., Ichikawa, C., Makino, K. et al. Long-term functional outcome of sacrococcygeal teratoma after resection in neonates and infants: a single-center experience. Pediatr Surg Int 36, 1327–1332 (2020). https://doi.org/10.1007/s00383-020-04752-7

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  • DOI: https://doi.org/10.1007/s00383-020-04752-7

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