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Pediatric arteriovenous malformation: University of Toronto experience using stereotactic radiosurgery

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Abstract

Introduction and background

Arteriovenous malformations (AVMs) are congenital vascular lesions of the brain, which behave differently in pediatric population compared to adults. Treatment of pediatric AVMs includes a combination of microsurgery, embolization and radiation therapies. However, the role of radiosurgery in the treatment of pediatric AVMs is not fully accepted because of concerns regarding the long-term effects of radiation on the pediatric brain.

Discussion

In this study, we review our experience at the University of Toronto with treating pediatric AVMs using linear accelerator-based (LINAC) radiosurgery over the past 15 years. We report our results, obliteration rates, and complications on a total of 40 patients. In addition, we provide a review of series published to date combined with our own results to determine whether radiosurgery is a safe and reasonable treatment modality for pediatric AVMs.

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Authors and Affiliations

  1. Division of Neurosurgery, Sunnybrook Health Sciences Centre (SHSC), Suite A129, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada

    Gelareh Zadeh, Yuri M. Andrade-Souza & Michael L. Schwartz

  2. Department of Radiation Oncology, Toronto-Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, ON, Canada

    May N. Tsao & Daryl Scora

  3. Department of Radiology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Derek Armstrong

  4. Division of Neurosurgery, Hospital for Sick Children, 555 University Ave., Toronto, ON, M5G1X8, Canada

    Robin Humphreys, James Rutka, James Drake & Peter Dirks

Authors
  1. Gelareh Zadeh
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  2. Yuri M. Andrade-Souza
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  3. May N. Tsao
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  4. Daryl Scora
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  5. Derek Armstrong
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  6. Robin Humphreys
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  7. James Rutka
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  8. James Drake
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  9. Peter Dirks
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  10. Michael L. Schwartz
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Corresponding author

Correspondence to Michael L. Schwartz.

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Zadeh, G., Andrade-Souza, Y.M., Tsao, M.N. et al. Pediatric arteriovenous malformation: University of Toronto experience using stereotactic radiosurgery. Childs Nerv Syst 23, 195–199 (2007). https://doi.org/10.1007/s00381-006-0207-3

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  • DOI: https://doi.org/10.1007/s00381-006-0207-3

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