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Evaluation of sexual function in women at two stages of multiple sclerosis

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Abstract

Purpose

In the present study, we aimed to evaluate the sexual function in patients with multiple sclerosis (MS) who were examined in two subgroups and compare the results to the control group with a validated questionnaire.

Methods

A total of 23 consecutive female MS patients divided into groups with relapsing-remitting MS (RRMS) and secondary progressive MS (SPMS) and 45 healthy control subjects were included into the study. The inclusion criteria were as follows: Definite MS, age between 18 and 60 years and an Expanded Disability Status Scale (EDSS) score of <8. The neurologic impairment, the disability and the independence of the patient, and cognitive performances were measured, and also the effect of MS is evaluated by EDSS.

Results

No statistically significant difference was found between two groups. FSFI scores in both groups were significantly lower than the control group. Domain scores for desire, arousal, orgasm, pain, lubrication and satisfaction measured between RRMS and SPMS patients showed no significant difference. Comparing each domain score for arousal, orgasm and satisfaction revealed significantly lower scores in RRMS and SPMS patients compared to control group.

Conclusions

In this study, we detected statistically significant decrease in FSFI scores in two groups of MS compared to healthy controls. We could not define a difference in sexual function in different stages of MS in women and a statistically significant negative correlation between EDSS and FSFI scores in the two subgroups of MS.

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References

  1. Laumann EO, Paik A, Rosen RC (1999) Sexual dysfunction in the United States, prevalence and predictors. JAMA 281:537–544

    Article  PubMed  CAS  Google Scholar 

  2. Raina R, Pahlajani G, Khan S, Gupta S, Agarwal A, Zippe CD (2007) Female sexual dysfunction: classification, pathophysiology and management. Fertil Steril 88(5):1273–1284

    Article  PubMed  Google Scholar 

  3. Zorzon M, Zivadinov R, Bosco A et al (1999) Sexual dysfunction in multiple sclerosis: a case-control study. Frequency and comparison of groups. Mult Scler 5(6):418–427

    PubMed  CAS  Google Scholar 

  4. Zivadinov R, Zorzon M, Bosco A et al (1999) Sexual dysfunction in multiple sclerosis: II. Correlation analysis. Mult Scler 5(6):428–431

    PubMed  CAS  Google Scholar 

  5. Nortwedt MW, Riise T, Myhr KM, Landtblom AM, Bakke A, Nyland HI (2001) Reduced quality of life among multiple sclerosis patients with sexual disturbance and bladder dysfunction. Mult Scler 7:231–235

    Google Scholar 

  6. Vas J (1969) Sexual impotence and some autonomic disturbances in men with multiple sclerosis. Acta Neurol Scand 45:166–182

    Article  PubMed  CAS  Google Scholar 

  7. Lilius HG, Valhonen EJ, Eikstrom J (1976) Sexual problems in patients suffering from multiple sclerosis. Scand J Soc Med 4:41–44

    PubMed  CAS  Google Scholar 

  8. Lundberg PO (1981) Sexual dysfunction in female patients with multiple sclerosis. Int Rehabil Med 3:32–34

    PubMed  CAS  Google Scholar 

  9. Minderhoud JM, Leemhuis JG, Kremer J, Laban E, Smits PM (1984) Sexual disturbances arising from multiple sclerosis. Acta Neurol Scand 70:299–306

    Article  PubMed  CAS  Google Scholar 

  10. Szasz G, Paty D, Maurice WL (1984) Sexual dysfunctions in multiple sclerosis. Ann N Y Acad Sci 436:443–452

    Article  PubMed  CAS  Google Scholar 

  11. Valleroy ML, Kraft GH (1984) Sexual dysfunction in multiple sclerosis. Arch Phys Med Rehabil 65:125–128

    PubMed  CAS  Google Scholar 

  12. Stenager E, Stenager EN, Jensen K (1992) Sexual aspects of multiple sclerosis. Semin Neurol 12:120–124

    Article  PubMed  CAS  Google Scholar 

  13. Hulter BM, Lundberg PO (1995) Sexual function in women with advanced multiple sclerosis. J Neurol Neurosurg Psychiatry 59:83–86

    Article  PubMed  CAS  Google Scholar 

  14. Mattson D, Petrie M, Srivastava DK, McDermott M (1995) Multiple sclerosis. Sexual dysfunction and its response to medications. Arch Neurol 52:862–868

    Article  PubMed  CAS  Google Scholar 

  15. Bakke A, Myhr KM, Gronning M, Nyland H (1996) Bladder, bowel and sexual dysfunction in patients with multiple sclerosis. Acohort study. Scand J Chron Nephrol Suppl 179:61–66

    CAS  Google Scholar 

  16. Barak Y, Achiron A, Elizur A, Gabbay U, Noy S, Sarova-Pinhas I (1996) Sexual dysfunction in relapsing-remitting multiple sclerosis: magnetic resonance imaging, clinic and psychologic correlates. J Psychiatry Neurosci 21:255–258

    PubMed  CAS  Google Scholar 

  17. Zivadinov R, Zorzon M, Locatelli L et al (2003) Sexual dysfunction in multiple sclerosis: a MRI, neurophysiological and urodynamic study. J Neurol Sci 210(1–2):73–76

    Article  PubMed  Google Scholar 

  18. Poser CM, Paty DW, Scheinberg L et al (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 12:227–231

    Article  Google Scholar 

  19. Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 33:1444–1452

    Article  PubMed  CAS  Google Scholar 

  20. Aygin D, Eti AF (2005) Kadın cinsel işlev ölçeğinin Türkçe’ye uyarlanması. Türkiye Klinikleri J Med Sci 25:393–399

    Google Scholar 

  21. Rosen R, Brown C, Heiman J et al (2000) The female sexual function index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther 26:191–208

    Article  PubMed  CAS  Google Scholar 

  22. Safarinejad MR (2006) Female sexual dysfunction in a population-based study in Iran: prevalance and associated risk factors. Int J Impot Res 18(4):382–395

    Article  PubMed  CAS  Google Scholar 

  23. DasGupta R, Fowler CJ (2003) Bladder, bowel and sexual dysfunction in multiple sclerosis. Management strategies. Drugs 63(2):153–166

    Article  PubMed  CAS  Google Scholar 

  24. Rosen RC, Taylor J, Leiblum SR, Bachmann GA (1993) Prevalence of sexual dysfunction in women: results of a survey study of 329 women in an outpatient gynecological clinic. J Sex Marital Ther 19:171–188

    Article  PubMed  CAS  Google Scholar 

  25. Goldmeier D, Judd A, Shroeder K (2000) Prevalence of sexual dysfunction in new heterosexual attenders at a central London genitourinary medicine clinic in 1998. Sex Transm Infect 76:208–209

    Article  PubMed  CAS  Google Scholar 

  26. Nappi R, Salonia A, Traish AM, Van Lunsen RH, Vardi Y, Kadioglu A, Goldstein I (2005) Clinical biologic pathophysiologies of women’s sexual dysfunction. J Sex Med 2(1):4–25

    Article  PubMed  Google Scholar 

  27. Katz A (2011) Multiple sclerosis and sexuality. Am J Nurs 111(7):65–68

    Article  PubMed  Google Scholar 

  28. Hulter BM, Lundberg PO (1995) Sexual function in women with advanced multiple sclerosis. J Neurol Neurosurg Psychiatry 59:83–86

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

We thank Mete Ozcan for statistical analysis.

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Authors and Affiliations

  1. Department of Urology, Faculty of Medicine, Firat University, Elazig, Turkey

    Fatih Firdolas, Tunc Ozan, Rahmi Onur & Irfan Orhan

  2. Department of Neurology, Faculty of Medicine, Firat University, Elazig, Turkey

    Serpil Bulut

  3. Üroloji Kliniği, Fırat Üniversitesi Hastanesi, Elazig, 23100, Turkey

    Fatih Firdolas

Authors
  1. Fatih Firdolas
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  2. Tunc Ozan
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  3. Rahmi Onur
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  5. Irfan Orhan
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Correspondence to Fatih Firdolas.

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Firdolas, F., Ozan, T., Onur, R. et al. Evaluation of sexual function in women at two stages of multiple sclerosis. World J Urol 31, 929–933 (2013). https://doi.org/10.1007/s00345-012-0891-4

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  • DOI: https://doi.org/10.1007/s00345-012-0891-4

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