Skip to main content
Log in

Ektopien des Mammagewebes

Ectopia of mammary tissue

  • Schwerpunkt: Ektopes Gewebe
  • Published:
Der Pathologe Aims and scope Submit manuscript

Zusammenfassung

Ektopien des Mammagewebes können die gesamte Brust (akzessorische Mamma), den Drüsenkörper ohne Mamille (aberrierende Mamma) oder nur die Mamille betreffen (Polythelie). Sie entwickeln sich entlang der von der vorderen Axillarfalte bis in die Vulva reichenden, als Milchleiste bezeichneten embryonalen Anlage, sehr selten auch außerhalb davon. Die häufigsten Lokalisationen sind die Axilla, die reguläre Mamma und ihre unmittelbare Nachbarschaft. Von ektopen Mammagewebe ausgehende Tumoren wie Fibroadenome und Karzinome sind in Einzelfällen beschrieben.

Abstract

Ectopic breast tissue may represent the complete breast (accessory breast), glandular tissue without areola or nipple (aberrant breast tissue), or exclusively the nipple (polythelia). Localization is along the embryonic milk ridge extending from the axilla to the vulva. Only rarely, is ectopic tissue found outside of the milk ridge. Most frequently affected are the axilla, the breast itself, and its close neighbourhood. Ectopic breast tissue may rarely give rise to tumours such as fibroadenoma or carcinoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4

Literatur

  1. Bässler R (1984) Pathologie der Brustdrüse. In: Remmele W (Hrsg) Pathologie, Bd. 3. Springer, Berlin, Heidelberg, New York, S 315

    Chapter  Google Scholar 

  2. Carter JE, Mizell KN, Tucker JA (2008) Mammary-type fibroepithelial neoplasms of the vulva: a case report and review of the literature. J Cutan Pathol 35:246–249

    PubMed  Google Scholar 

  3. Chung-Park M, Zheng Liu C, Giampoli EJ, Emery JD, Shalodi A (2002) Mucinous adenocarcinoma of ectopic breast tissue of the vulva. Arch Pathol Lab Med 126:1216–1218

    PubMed  Google Scholar 

  4. Dzodic R, Stanojevic B, Saenko V, Nakashima M, Markovic I, Pupic G, Buta M, Inic M, Rogounovitch T, Yamashita S (2010) Intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast: a case report and review of the literature. Diagn Pathol 5:17

    Article  PubMed  PubMed Central  Google Scholar 

  5. Edlow DW, Carter D (1973) Heterotopic epithelium in axillary lymph nodes: report of a case and review of the literature. Am J Clin Pathol 59:666–673

    Article  PubMed  CAS  Google Scholar 

  6. Fellegara G, Carcangiu ML, Rosai J (2011) Benign epithelial inclusions in axillary lymph nodes: report of 18 cases and review of the literature. Am J Surg Pathol 35:1123–1133

    Article  PubMed  Google Scholar 

  7. Francone E, Nathan MJ, Murelli F, Bruno MS, Traverso E, Friedman D (2013) Ectopic breast cancer: case report and review of the literature. Aesthetic Plast Surg 37:746–749

    Article  PubMed  Google Scholar 

  8. Intra M, Maggioni A, Sonzogni A, De Cicco C, Machado LS, Sagona A, Talakhadze N (2006) A rare association of synchronous intraductal carcinoma of the breast and invasive carcinoma of ectopic breast tissue of the vulva: case report and literature review. Int J Gynecol Cancer 16(Suppl 1):428–433

    Article  PubMed  Google Scholar 

  9. Kalyani R, Srinivas MV, Veda P (2014) Vulval fibroadenoma—a report of two cases with review of literature. Int J Biomed Sci 10:143–145

    PubMed  PubMed Central  CAS  Google Scholar 

  10. Kenney RD, Flippo JL, Black EB (1987) Supernumerary nipples and renal anomalies in neonates. Am J Dis Child 141(9):987–988. https://doi.org/10.1001/archpedi.1987.04460090064026

    Article  PubMed  CAS  Google Scholar 

  11. Lee J, Jung JH, Kim WW, Hwang SO, Kang JG, Baek J, Kim HJ, Park JY, Jeong JY, Lim JY, Park HY (2014) Ductal carcinoma arising from ectopic breast tissue following microcalcification observed on screening mammography: a case report and review of the literature. J Breast Cancer 17:393–396

    Article  PubMed  PubMed Central  Google Scholar 

  12. Lopes G, DeCesare T, Ghurani G, Vincek V, Jorda M, Glück S, Silva O (2006) Primary ectopic breast cancer presenting as a vulvar mass. Clin Breast Cancer 7:278–279

    Article  PubMed  Google Scholar 

  13. Mannan AA, Kahvic M, Aziz AH (2010) Phyllodes tumor of the vulva: Report of a rare case and review of the literature. Am J Dermatopathol 32:384–386

    Article  PubMed  Google Scholar 

  14. Nardello SM, Kulkarni N, Aggon A, Boraas M, Sigurdson ER, Bleicher RJ (2015) Invasive mucinous carcinoma arising in ectopic axillary breast tissue: a case report and literature review. Am J Case Rep 16:153–159

    Article  PubMed  PubMed Central  Google Scholar 

  15. Nihon-Yanagi Y, Ueda T, Kameda N, Okazumi S (2011) A case of ectopic breast cancer with a literature review. Surg Oncol 20(1):35–42

    Article  PubMed  Google Scholar 

  16. Piura B, Gemer O, Rabinovich A, Yanai-Inbar I (2002) Primary breast carcinoma of the vulva: case report and review of literature. Eur J Gynaecol Oncol 23:21–24

    PubMed  CAS  Google Scholar 

  17. Radner H, Berger A, Schmid KO (1987) Mamma supernumeraria dorsalis interscapularis (paravertebralis). Ein klinisch-pathologischer Fallbericht mit Literaturübersicht. Pathologe 8:310–315

    PubMed  CAS  Google Scholar 

  18. Rosen PP (2009) Rosen’s breast pathology. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  19. Silton RM (1979) More glandular inclusions. Am J Surg Pathol 3:285–286

    Article  PubMed  CAS  Google Scholar 

  20. Troupis T, Michalinos A, Skandalakis P (2012) Intramammary lymph nodes: a question seeking for an answer or an answer seeking for a question? Breast 21:615–620

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H. H. Kreipe.

Ethics declarations

Interessenkonflikt

H. H. Kreipe und M. Christgen geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

Additional information

Schwerpunktherausgeber

W. Saeger, Hamburg

K.W. Schmid, Essen

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kreipe, H.H., Christgen, M. Ektopien des Mammagewebes. Pathologe 39, 398–401 (2018). https://doi.org/10.1007/s00292-018-0468-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00292-018-0468-0

Schlüsselwörter

Keywords

Navigation