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Percutaneous Intraductal Microwave Ablation and Self-expandable Metallic Stenting: A New Treatment Method for Malignant Extrahepatic Biliary Obstruction

  • Clinical Investigation
  • Biliary
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Purpose

To evaluate the patency and clinical efficacy of percutaneous intraductal microwave ablation (PIMWA) and uncovered self-expandable metallic stents (USEMs) in inoperable malignant extrahepatic biliary obstruction.

Materials and methods

The procedures to be performed on patients with malignant inoperable extrahepatic biliary obstruction were decided by a multidisciplinary team including an interventional radiologist. In our study, 141 patients were evaluated retrospectively. Twenty-one patients who underwent PIMWA + USEMs with the MedWaves AveCure microwave system (AveCure® Intelligent Controller and Super-Flex Smart Catheter) and met the inclusion criteria were included in the study. Complications related to the intervention, stent patency, survival time, serum bilirubin levels, and the general condition of the patients were noted.

Results

The median stent patency and the median survival time were 108 and 143 days, respectively. The rates of 30-day, 2-month, 6-month and 8-month survival were 95.2%, 85.7%, 38.1%, and 14.3%, respectively.

Conclusion

The PIMWA + USEMs procedure is a safe, effective, and minimally invasive alternative palliative treatment method in patients with malignant inoperable extrahepatic biliary obstruction.

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Acknowledgements

We would like to thank Mehmet Serkan Gür MD and Volkan Çakır MD from our interventional radiology department for their expert advice and encouragement throughout the manuscript preparation.

Funding

This study was not supported by any funding.

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Authors and Affiliations

  1. Department of Interventional Radiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, 35360, İzmir, Turkey

    Rıdvan Pekçevik & Ömür Ballı

Authors
  1. Rıdvan Pekçevik
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  2. Ömür Ballı
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Correspondence to Rıdvan Pekçevik.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For the study, approval from the ethics committee of our hospital with the 326 IRB number were obtained.

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Informed consent was obtained from all individual participants included in the study.

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Consent for publication was obtained for every individual person’s data included in the study.

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Pekçevik, R., Ballı, Ö. Percutaneous Intraductal Microwave Ablation and Self-expandable Metallic Stenting: A New Treatment Method for Malignant Extrahepatic Biliary Obstruction. Cardiovasc Intervent Radiol 44, 110–117 (2021). https://doi.org/10.1007/s00270-020-02684-2

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  • DOI: https://doi.org/10.1007/s00270-020-02684-2

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