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CT-Guided Percutaneous Needle Biopsy in Patients with Suspected Retroperitoneal Fibrosis: A Retrospective Cohort Study

  • Clinical Investigation
  • Non-Vascular Interventions
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Purpose

The outcome of CT-guided biopsy in patients with suspected retroperitoneal fibrosis (RF), regarded as technically challenging, remains unclear. This study aimed to evaluate the results of CT-guided biopsy in patients with lesions considered in the differential diagnosis of RF and compare them with results from patients with other retroperitoneal lesions.

Materials and Methods

Patients who underwent CT-guided biopsy of retroperitoneal lesions between January 2010 and September 2018 were retrospectively reviewed. The study cohort with retroperitoneal lesions surrounding the infra-abdominal aorta, iliac vessels, and/or ureters was divided into two groups: Group F included patients with lesions for which RF was considered in the differential diagnosis, and Group C comprised patients with a retroperitoneal mass or lymphadenopathy. Lesion size and depth, and biopsy details including technical success, position, procedure time, diagnostic yield, and complications between the two groups were compared.

Results

Group F included 27 patients (mean age 68.5 years ± 11.6, 17 male) and Group C 30 patients (mean age 65.0 years ± 11.8, 16 male). The short axis was significantly smaller in Group F than in Group C (19 mm vs 26 mm, P = 0.041), and procedure time was significantly longer in Group F than in Group C (31.5 min ± 13.2 vs 20.3 min ± 8.4, P = 0.001). Technical success rate (93% vs 100%), accuracy (93% vs 93%), and complications (3.7% vs 10%) between Groups F and C were not significantly different.

Conclusions

CT-guided biopsy of patients with suspected RF is considered safe and effective.

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Abbreviations

CT:

Computed tomography

IgG:

Immunoglobulin

PNB:

Percutaneous needle biopsy

RF:

Retroperitoneal fibrosis

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Acknowledgements

We thank Hugh McGonigle, from Edanz Group (www.edanzediting.com/ac), for editing a draft of this manuscript.

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Authors and Affiliations

  1. Department of Interventional Radiology, Yokohama Rosai Hospital, 3211, Kozukue-cho, Kouhoku-Ku, Yokohama, Kanagawa, 222-0036, Japan

    Yuya Koike & Seishi Matsui

  2. Department of Radiology, Yokohama Rosai Hospital, Yokohama, Japan

    Koichiro Takase & Hiromitsu Tannai

Authors
  1. Yuya Koike
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  2. Seishi Matsui
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  3. Koichiro Takase
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  4. Hiromitsu Tannai
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Corresponding author

Correspondence to Yuya Koike.

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The authors have no conflict of interest to disclose.

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For this type of study formal consent is not required.

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This study has obtained IRB approval and the need for informed consent was waived.

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Consent for publication was obtained for every individual person’s data included in the study.

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Koike, Y., Matsui, S., Takase, K. et al. CT-Guided Percutaneous Needle Biopsy in Patients with Suspected Retroperitoneal Fibrosis: A Retrospective Cohort Study. Cardiovasc Intervent Radiol 42, 1434–1440 (2019). https://doi.org/10.1007/s00270-019-02266-x

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  • DOI: https://doi.org/10.1007/s00270-019-02266-x

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