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Cholangiojejunostomy Using a Novel Magnamosis Device: Initial Clinical Results

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Abstract

Background

Cholangiojejunostomy (CJ) is a popular operation; however, no specific anastomotic device is available. A novel magnamosis device for CJ was developed in 2017; here, we evaluated the feasibility and safety of the device.

Methods

Between January 2017 and December 2019, 23 patients who underwent CJ using a novel magnamosis device were enrolled. For the CJ: the parent magnet was placed in the proximal duct, and the purse–string suture was tightened over the rod of the parent magnet. The magnamosis device was introduced into the jejunum, and the mandrel penetrated the jejunum at the anastomotic site, before insertion into the rod of the parent magnet. After rotating the knob, the distance between two magnets was shortened enough to achieve coupling.

Results

Sixteen patients (69.6%) underwent open CJ, while 7 (30.4%) underwent laparoscopic CJ; 21 patients (91.3%) underwent choledochojejunostomy, and 2 (8.7%) underwent right or left hepatic duct jejunostomy. The mean time for completion of CJ was 9.2±2.5 min; it was significantly shorter for open CJ than for the laparoscopic way (8±1.2 min vs. 11.8±2.5 min, P<0.05). Only one patient (4.3%) suffered bile leakage after operation and was cured by conservative treatment. The magnets were discharged with a postoperative duration of 66.7±47.2 days, with a 100% expulsion rate. After a median follow-up of 15 months, only one patient (4.3%) developed inflammatory anastomotic stricture.

Conclusion

The novel magnamosis device is a simple, safe, and effective modality for CJ.

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Acknowledgements

The authors thank the staff and students from the Hepatobiliary Surgery Department, National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, and Shaanxi Province Center for Regenerative Medicine and Surgery Engineering Research for their help and for providing all facilities needed to carry out this study.

Funding

This work was supported by National Natural Science Foundation of China (grant number: 81470896).

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Author notes

  1. Yu Li and Xue-min Liu contribute equally to the work.

Authors and Affiliations

  1. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, China

    Yu Li, Xue-min Liu, Xu-feng Zhang, Ji-gang Bai & Yi Lv

  2. National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi’an, 710061, China

    Yu Li, Xue-min Liu, Hong-ke Zhang, Xu-feng Zhang, Bo Tang & Yi Lv

  3. Shaanxi Province Center for Regenerative Medicine and Surgery Engineering Research, Xi’an, 710061, China

    Yu Li, Xue-min Liu, Hong-ke Zhang, Xu-feng Zhang, Bo Tang & Yi Lv

Authors
  1. Yu Li
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  2. Xue-min Liu
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  3. Hong-ke Zhang
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  4. Xu-feng Zhang
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Corresponding author

Correspondence to Yi Lv.

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Ethical approval

Ethical consent was given by the ethical committee at the First Affiliated Hospital of Xi’an Jiaotong University (XJTU1AF2015LSL-046).

Informed consent

All participants eligible for inclusion received full explanation of the protocol and provided informed consent. The study was carried out in accordance with the Declaration of Helsinki.

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Li, Y., Liu, Xm., Zhang, Hk. et al. Cholangiojejunostomy Using a Novel Magnamosis Device: Initial Clinical Results. World J Surg 45, 3138–3145 (2021). https://doi.org/10.1007/s00268-021-06196-z

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  • DOI: https://doi.org/10.1007/s00268-021-06196-z

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