Skip to main content
Log in

Prophylactic inferior vena cava filters for operative pelvic fractures: a twelve year experience

  • Original Paper
  • Published:
International Orthopaedics Aims and scope Submit manuscript

Abstract

Introduction

Conflicting evidence exists regarding the role of inferior vena cava filters (IVCFs) in the prevention of pulmonary embolism. The aim of this study was to review an institutional policy of prophylactic IVCF placement in all operative pelvic and acetabular fractures as a means of preventing PE by comparing it to a historical prepolicy period of significantly less aggressive IVCF placement.

Methods

The trauma registry of a single level 1 trauma center was retrospectively queried for all pelvic or acetabular fractures for the prepolicy and intervention periods as defined as January 2003–December 2008 and January 2009–December 2014, respectively—yielding 231 patients for analysis. The primary and secondary outcomes measured were the incidence of PE and deep vein thrombosis.

Results

The rate of prophylactic IVCF insertion significantly increased during the study period (p < 0.001). The incidence of pulmonary embolism (1.8% vs. 5.1%, p = 0.351) and DVT (19.3% vs. 10.3%, p = 0.231) were not significantly different when comparing the prepolicy and intervention cohorts. In patients with operative fractures, a nonsignificant trend of increasing incidence of DVTs was appreciated in patients with a prophylactic IVCF versus those without prophylactic IVCF (13 vs. 2, p = 0.222).

Discussion

A policy of increased use of prophylactic IVCFs in patients with operative pelvic and acetabular fractures failed to reduce the incidence of PE or DVT. In contrast, several case reports and institutional series have published several risks associated with IVCF placement including failure to retrieve temporary IVCF.

Conclusion

The benefit of prophylactic IVCF in this patient population is unclear.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Sharma OP, Oswanski MF, Joseph RJ, Tonui P, Westrick L, Raj SS, Tatchell T, Waite PJ, Gandaio A (2007) Venous thromboembolism in trauma patients. Am Surg 73:1173–1180

    PubMed  Google Scholar 

  2. Buerger PM, Peoples JB, Lemmon GW, McCarthy MC (1993) Risk of pulmonary emboli in patients with pelvic fractures. Am Surg 59:505–508

    CAS  PubMed  Google Scholar 

  3. Godoy Monzon D, Iserson KV, Cid A, Vazquez JA (2012) Oral thromboprophylaxis in pelvic trauma: a standardized protocol. J Emerg Med 43:612–617. https://doi.org/10.1016/j.jemermed.2011.09.006

    Article  PubMed  Google Scholar 

  4. Montgomery KD, Geerts WH, Potter HG, Helfet DL (1996) Thromboembolic complications in patients with pelvic trauma. Clin Orthop Relat Res :68–87. https://doi.org/10.1097/00003086-199608000-00010

    Article  Google Scholar 

  5. Kim JW, Oh CW, Oh JK, Baek SG, Lee BJ, Hong HP, Min WK (2014) The incidence and the risk factors of venous thromboembolism in Korean patients with pelvic or acetabular fractures. J Orthop Sci 19:471–477. https://doi.org/10.1007/s00776-014-0553-z

    Article  PubMed  Google Scholar 

  6. Carlin AM, Tyburski JG, Wilson RF, Steffes C (2002) Prophylactic and therapeutic inferior vena cava filters to prevent pulmonary emboli in trauma patients. Arch Surg 137:521–525 discussion 525-527

    Article  PubMed  Google Scholar 

  7. Duszak R Jr, Parker L, Levin DC, Rao VM (2011) Placement and removal of inferior vena cava filters: national trends in the Medicare population. J Am Coll Radiol 8:483–489. https://doi.org/10.1016/j.jacr.2010.12.021

    Article  PubMed  Google Scholar 

  8. Moore PS, Andrews JS, Craven TE, Davis RP, Corriere MA, Godshall CJ, Edwards MS, Hansen KJ (2010) Trends in vena caval interruption. J Vasc Surg 52:118–125 e113; discussion 125-116. https://doi.org/10.1016/j.jvs.2009.09.067

    Article  PubMed  Google Scholar 

  9. Gosin JS, Graham AM, Ciocca RG, Hammond JS (1997) Efficacy of prophylactic vena cava filters in high-risk trauma patients. Ann Vasc Surg 11:100–105. https://doi.org/10.1007/s100169900017

    Article  CAS  PubMed  Google Scholar 

  10. Rogers FB, Shackford SR, Wilson J, Ricci MA, Morris CS (1993) Prophylactic vena cava filter insertion in severely injured trauma patients: indications and preliminary results. J Trauma 35:637–641 discussion 641-632

    Article  CAS  PubMed  Google Scholar 

  11. Khansarinia S, Dennis JW, Veldenz HC, Butcher JL, Hartland L (1995) Prophylactic greenfield filter placement in selected high-risk trauma patients. J Vasc Surg 22:231–235 discussion 235-236

    Article  CAS  PubMed  Google Scholar 

  12. Webb LX, Rush PT, Fuller SB, Meredith JW (1992) Greenfield filter prophylaxis of pulmonary embolism in patients undergoing surgery for acetabular fracture. J Orthop Trauma 6:139–145

    Article  CAS  PubMed  Google Scholar 

  13. Langan EM 3rd, Miller RS, Casey WJ 3rd, Carsten CG 3rd, Graham RM, Taylor SM (1999) Prophylactic inferior vena cava filters in trauma patients at high risk: follow-up examination and risk/benefit assessment. J Vasc Surg 30:484–488

    Article  PubMed  Google Scholar 

  14. Rogers FB, Cipolle MD, Velmahos G, Rozycki G, Luchette FA (2002) Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group. J Trauma 53:142–164

    Article  PubMed  Google Scholar 

  15. Gould MK, Garcia DA, Wren SM, Karanicolas PJ, Arcelus JI, Heit JA, Samama CM, American College of Chest P (2012) Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141:e227S–e277S. https://doi.org/10.1378/chest.11-2297

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Hemmila MR, Osborne NH, Henke PK, Kepros JP, Patel SG, Cain-Nielsen AH, Birkmeyer NJ (2015) Prophylactic inferior vena cava filter placement does not result in a survival benefit for trauma patients. Ann Surg 262:577–585. https://doi.org/10.1097/SLA.0000000000001434

    Article  PubMed  Google Scholar 

  17. Cherry RA, Nichols PA, Snavely TM, David MT, Lynch FC (2008) Prophylactic inferior vena cava filters: do they make a difference in trauma patients? J Trauma 65:544–548. https://doi.org/10.1097/TA.0b013e31817f980f

    Article  PubMed  Google Scholar 

  18. Rogers FB, Shackford SR, Ricci MA, Wilson JT, Parsons S (1995) Routine prophylactic vena cava filter insertion in severely injured trauma patients decreases the incidence of pulmonary embolism. J Am Coll Surg 180:641–647

    CAS  PubMed  Google Scholar 

  19. Rogers FB, Shackford SR, Ricci MA, Huber BM, Atkins T (1997) Prophylactic vena cava filter insertion in selected high-risk orthopaedic trauma patients. J Orthop Trauma 11:267–272

    Article  CAS  PubMed  Google Scholar 

  20. McMurtry AL, Owings JT, Anderson JT, Battistella FD, Gosselin R (1999) Increased use of prophylactic vena cava filters in trauma patients failed to decrease overall incidence of pulmonary embolism. J Am Coll Surg 189:314–320

    Article  CAS  PubMed  Google Scholar 

  21. Gorman PH, Qadri SF, Rao-Patel A (2009) Prophylactic inferior vena cava (IVC) filter placement may increase the relative risk of deep venous thrombosis after acute spinal cord injury. J Trauma 66:707–712. https://doi.org/10.1097/TA.0b013e318188beba

    Article  PubMed  Google Scholar 

  22. Rajasekhar A, Lottenberg L, Lottenberg R, Feezor RJ, Armen SB, Liu H, Efron PA, Crowther M, Ang D (2011) A pilot study on the randomization of inferior vena cava filter placement for venous thromboembolism prophylaxis in high-risk trauma patients. J Trauma 71:323–328; discussion 328-329. https://doi.org/10.1097/TA.0b013e318226ece1

    Article  PubMed  Google Scholar 

  23. Antevil JL, Sise MJ, Sack DI, Sasadeusz KJ, Swanson SM, Rivera L, Lome BR, Weingarten KE, Kaminski SS (2006) Retrievable vena cava filters for preventing pulmonary embolism in trauma patients: a cautionary tale. J Trauma 60:35–40. https://doi.org/10.1097/01.ta.0000197607.23019.ab

    Article  PubMed  Google Scholar 

  24. Stein PD, Matta F, Hughes MJ (2018) Prophylactic inferior vena cava filters in patients with fractures of the pelvis or long bones. J Clin Orthop Trauma 9:175–180. https://doi.org/10.1016/j.jcot.2017.09.018

    Article  PubMed  Google Scholar 

  25. Young T, Tang H, Hughes R (2010) Vena caval filters for the prevention of pulmonary embolism. Cochrane Database Syst Rev:CD006212. https://doi.org/10.1002/14651858.CD006212.pub4

  26. Sarosiek S, Crowther M, Sloan JM (2013) Indications, complications, and management of inferior vena cava filters: the experience in 952 patients at an academic hospital with a level I trauma center. JAMA Intern Med 173:513–517. https://doi.org/10.1001/jamainternmed.2013.343

    Article  PubMed  Google Scholar 

  27. Decousus H, Leizorovicz A, Parent F, Page Y, Tardy B, Girard P, Laporte S, Faivre R, Charbonnier B, Barral FG, Huet Y, Simonneau G (1998) A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. Prevention du Risque d'Embolie Pulmonaire par Interruption Cave Study Group. N Engl J Med 338:409–415. https://doi.org/10.1056/NEJM199802123380701

    Article  CAS  PubMed  Google Scholar 

  28. Group PS (2005) Eight-year follow-up of patients with permanent vena cava filters in the prevention of pulmonary embolism: the PREPIC (Prevention du Risque d'Embolie Pulmonaire par Interruption Cave) randomized study. Circulation 112:416–422. https://doi.org/10.1161/CIRCULATIONAHA.104.512834

    Article  Google Scholar 

  29. Caplin DM, Nikolic B, Kalva SP, Ganguli S, Saad WE, Zuckerman DA, Society of Interventional Radiology Standards of Practice C (2011) Quality improvement guidelines for the performance of inferior vena cava filter placement for the prevention of pulmonary embolism. J Vasc Interv Radiol 22:1499–1506. https://doi.org/10.1016/j.jvir.2011.07.012

    Article  PubMed  Google Scholar 

  30. Owens CA, Bui JT, Knuttinen MG, Gaba RC, Carrillo TC, Hoefling N, Layden-Almer JE (2009) Intracardiac migration of inferior vena cava filters: review of published data. Chest 136:877–887. https://doi.org/10.1378/chest.09-0153

    Article  PubMed  Google Scholar 

  31. Slobogean GP, Lefaivre KA, Nicolaou S, O'Brien PJ (2009) A systematic review of thromboprophylaxis for pelvic and acetabular fractures. J Orthop Trauma 23:379–384. https://doi.org/10.1097/BOT.0b013e3181a5369c

    Article  PubMed  Google Scholar 

  32. Velmahos GC, Kern J, Chan LS, Oder D, Murray JA, Shekelle P (2000) Prevention of venous thromboembolism after injury: an evidence-based report--part II: analysis of risk factors and evaluation of the role of vena caval filters. J Trauma 49:140–144

    Article  CAS  PubMed  Google Scholar 

  33. Paffrath T, Wafaisade A, Lefering R, Simanski C, Bouillon B, Spanholtz T, Wutzler S, Maegele M, Trauma Registry of DGU (2010) Venous thromboembolism after severe trauma: incidence, risk factors and outcome. Injury 41:97–101. https://doi.org/10.1016/j.injury.2009.06.010

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We would like to recognize Kathleen Maguire MD, Daniel Spielman BA, Jimmy Chan MD, and Dordaneh Sugano BS for their assistance in data collection for this manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Wayne B. Cohen-Levy.

Ethics declarations

Institutional Review Board approval was obtained from the Albert Einstein College of Medicine prior to conducting the study.

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cohen-Levy, W.B., Liu, J., Sen, M. et al. Prophylactic inferior vena cava filters for operative pelvic fractures: a twelve year experience. International Orthopaedics (SICOT) 43, 2831–2838 (2019). https://doi.org/10.1007/s00264-019-04384-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00264-019-04384-0

Keywords

Navigation