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Paraneoplastic syndrome demonstrated on 99mTc-HMDP bone scan

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Abstract

A 23-year-old man, with no relevant medical history, presented with inflammatory peripheral and axial polyarthritis, wrist pain, and persistent low-grade fever for the past 4 months. A bone scintigraphy showed intense periosteal early and delayed uptake in long bones, with normal uptake in the spine, pelvis, and rib cage, and no clear focus of hypermetabolism. CT scan revealed a mediastinal mass. A biopsy of the mass demonstrated Hodgkin lymphoma with bulky disease. This paraneoplastic syndrome as the first sign of intrathoracic Hodgkin’s disease is rare.

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Authors and Affiliations

  1. Service de Médecine Nucléaire, Hospices Civils de Lyon, Lyon, France

    Sophie Lancelot, Francesco Giammarile & Agnes Tescaru

  2. Lyon Neuroscience Research Center, INSERM, CNRS, Université Claude Bernard Lyon 1, Lyon, France

    Sophie Lancelot

  3. Equipe Mixte de Recherche, Université Claude Bernard Lyon 1, 3738, Lyon, France

    Francesco Giammarile

  4. Médecine Nucléaire Groupement Hospitalier Est, 59, boulevard Pinel, 69677, Bron Cedex, France

    Francesco Giammarile

Authors
  1. Sophie Lancelot
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  2. Francesco Giammarile
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  3. Agnes Tescaru
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Corresponding author

Correspondence to Francesco Giammarile.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institution and with the principles of the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Lancelot, S., Giammarile, F. & Tescaru, A. Paraneoplastic syndrome demonstrated on 99mTc-HMDP bone scan. Eur J Nucl Med Mol Imaging 43, 2271–2272 (2016). https://doi.org/10.1007/s00259-016-3471-9

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  • DOI: https://doi.org/10.1007/s00259-016-3471-9

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